A comprehensive review on genomics, systems biology and structural biology approaches for combating antimicrobial resistance in ESKAPE pathogens …

P Priyamvada, R Debroy, A Anbarasu… - World Journal of …, 2022 - Springer
In recent decades, antimicrobial resistance has been augmented as a global concern to
public health owing to the global spread of multidrug-resistant strains from different ESKAPE …

A critical review of datasets and computational suites for improving cancer theranostics and biomarker discovery

G Ashok, S Ramaiah - Medical Oncology, 2022 - Springer
Cancer has been constantly evolving and so is the research pertaining to cancer diagnosis
and therapeutic regimens. Early detection and specific therapeutics are the key features of …

[HTML][HTML] Statistics and network-based approaches to identify molecular mechanisms that drive the progression of breast cancer

MS Alam, MM Rahaman, A Sultana, G Wang… - Computers in Biology …, 2022 - Elsevier
Breast cancer (BC) is one of the most malignant tumors and the leading cause of cancer-
related death in women worldwide. So, an in-depth investigation on the molecular …

FN1 encoding fibronectin as a pivotal signaling gene for therapeutic intervention against pancreatic cancer

G Ashok, SK Miryala, MT Saju, A Anbarasu… - Molecular Genetics and …, 2022 - Springer
The delayed diagnosis of pancreatic cancer has resulted in rising mortality rate and low
survival rate that can be circumvented using potent theranostics biomarkers. The treatment …

FN1 and cancer‐associated fibroblasts markers influence immune microenvironment in clear cell renal cell carcinoma

G Ashok, S Ramaiah - The Journal of Gene Medicine, 2023 - Wiley Online Library
Background Altered tumor microenvironment (TME) is characterized in clear cell renal cell
carcinoma (ccRCC) as a result of the heterogeneity observed in the TME. Modulations in …

Translational protein RpsE as an alternative target for novel nucleoside analogues to treat MDR Enterobacter cloacae ATCC 13047: network analysis and molecular …

R Debroy, S Ramaiah - World Journal of Microbiology and Biotechnology, 2023 - Springer
The pathogenic Enterobacter cloacae subsp. cloacae str. ATCC 13047 has contemporarily
emerged as a multi-drug resistant strain. To formulate an effective treatment option …

Potential signature therapeutic biomarkers TOP2A, MAD2L1, and CDK1 in colorectal cancer: a systems biomedicine-based approach

P Priyamvada, S Ramaiah - Biochemical Genetics, 2024 - Springer
Colorectal cancer is the third deadliest and fourth most diagnosed cancer. It is
heterogeneously driven by varied mutations and mutagens, and thus, it is challenging for …

Comprehensive analysis on the diagnostic role of circulatory exosome‐based miR‐92a‐3p for osteoblastic metastases in prostate adenocarcinoma

G Ashok, R Das, A Anbarasu… - Journal of Molecular …, 2023 - Wiley Online Library
Prostate adenocarcinoma (PRAD) is the second leading cause of death in men and the key
factor that attributes to the severity and higher mortality rates is the tumor's ability to promote …

Cancer-biomarkers associated with sex hormone receptors and recent therapeutic advancements: a comprehensive review

S Anbarasu, A Anbarasu - Medical Oncology, 2023 - Springer
Hormones and its regulation plays vital role in causing breast, prostate, ovarian and
endometrial cancers collectively known as hormone-sensitive cancers. This review …

Network topology analysis of essential genes interactome of Helicobacter pylori to explore novel therapeutic targets

P Gollapalli, H Manjunatha, P Shetty - Microbial Pathogenesis, 2021 - Elsevier
The Helicobacter pylori chronic colonization produces a wide range of gastric diseases in
the gastric mucosa by abetting inflammation. Amidst coevolution and reorganization of its …