Altered glycosylation in cancer: A promising target for biomarkers and therapeutics

D Thomas, AK Rathinavel, P Radhakrishnan - Biochimica et Biophysica …, 2021 - Elsevier
Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …

Exploring the phytochemicals and anti-cancer potential of the members of Fabaceae family: A comprehensive review

M Usman, WR Khan, N Yousaf, S Akram, G Murtaza… - Molecules, 2022 - mdpi.com
Cancer is the second-ranked disease and a cause of death for millions of people around the
world despite many kinds of available treatments. Phytochemicals are considered a vital …

Structure-function and application of plant lectins in disease biology and immunity

A Mishra, A Behura, S Mawatwal, A Kumar… - Food and Chemical …, 2019 - Elsevier
Lectins are proteins with a high degree of stereospecificity to recognize various sugar
structures and form reversible linkages upon interaction with glyco-conjugate complexes …

Legume lectins: proteins with diverse applications

I Lagarda-Diaz, AM Guzman-Partida… - International journal of …, 2017 - mdpi.com
Lectins are a diverse class of proteins distributed extensively in nature. Among these
proteins; legume lectins display a variety of interesting features including antimicrobial; …

Lectins, interconnecting proteins with biotechnological/pharmacological and therapeutic applications

LCBB Coelho, PMS Silva, VLM Lima… - Evidence‐Based …, 2017 - Wiley Online Library
Lectins are proteins extensively used in biomedical applications with property to recognize
carbohydrates through carbohydrate‐binding sites, which identify glycans attached to cell …

Tumour-associated carbohydrate antigens in breast cancer

A Cazet, S Julien, M Bobowski, J Burchell… - Breast cancer …, 2010 - Springer
Glycosylation changes that occur in cancer often lead to the expression of tumour-
associated carbohydrate antigens. In breast cancer, these antigens are usually associated …

Lectins purified from medicinal and edible mushrooms: Insights into their antiviral activity against pathogenic viruses

YA El-Maradny, EM El-Fakharany… - International journal of …, 2021 - Elsevier
For thousands of years, fungi have been a valuable and promising source of therapeutic
agents for treatment of various diseases. Mushroom is a macrofungus which has been …

Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P-selectin ligands in …

CA Cooney, F Jousheghany, A Yao-Borengasser… - Breast cancer …, 2011 - Springer
Introduction We have previously demonstrated that chondroitin sulfate glycosaminoglycans
(CS-GAGs) on breast cancer cells function as P-selectin ligands. This study was performed …

[HTML][HTML] Diagnosis and management of ductal carcinoma in situ (DCIS).

BA Virnig, T Shamliyan, TM Tuttle… - Evidence report …, 2009 - europepmc.org
Diagnosis and management of ductal carcinoma in situ (DCIS). - Abstract - Europe PMC Sign in
| Create an account https://orcid.org Europe PMC Menu About Tools Developers Help Contact …

Glycobiology of cellular expiry: decrypting the role of glycan-lectin regulatory complex and therapeutic strategies focusing on cancer

AK Das, N Ghosh, A Mandal, PC Sil - Biochemical Pharmacology, 2023 - Elsevier
Often the outer leaflets of living cells bear a coat of glycosylated proteins, which primarily
regulates cellular processes. Glycosylation of such proteins occurs as part of their post …