miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis

CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

New insight into microRNA functions in cancer: oncogene–microRNA–tumor suppressor gene network

K Zhou, M Liu, Y Cao - Frontiers in molecular biosciences, 2017 - frontiersin.org
Tumorigenesis is a multi-step and complex process with multi-factors involved. Deregulated
oncogenes and tumor suppressor genes (TSGs) induced by genetic and epigenetic factors …

Analysis and validation of m6A regulatory network: a novel circBACH2/has-miR-944/HNRNPC axis in breast cancer progression

W Lv, Y Tan, M Xiong, C Zhao, Y Wang, M Wu… - Journal of Translational …, 2021 - Springer
Abstract Background N6-methyladenosine (m6A), the most abundant and reversible
modification of mRNAs in eukaryotes, plays pivotal role in breast cancer (BC) tumorigenesis …

HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells

CM Klinge, KM Piell, CS Tooley, EC Rouchka - Scientific reports, 2019 - nature.com
MicroRNAs are dysregulated in breast cancer. Heterogeneous Nuclear Ribonucleoprotein
A2/B1 (HNRNPA2/B1) is a reader of the N (6)-methyladenosine (m6A) mark in primary …

miR-142-5p enhances cisplatin-induced apoptosis in ovarian cancer cells by targeting multiple anti-apoptotic genes

X Li, W Chen, Y Jin, R Xue, J Su, Z Mu, J Li… - Biochemical …, 2019 - Elsevier
Chemotherapy is the preferred treatment for advanced ovarian cancer, but the 5-year
survival rate remains low partly because of the development of drug resistance. Although it …

Novel insights into miR-944 in cancer

J Shen, Q Wang, C Liang, X Su, Y Ke, Y Mao, J Fang… - Cancers, 2022 - mdpi.com
Simple Summary miR-944 is localized in intron 4 of TP63. ΔNp63 in intron 3 of TP63 recruits
the transcription factor AP-2 to promote miR-944 gene expression, which mediates …

microRNA-944 inhibits breast cancer cell proliferation and promotes cell apoptosis by reducing SPP1 through inactivating the PI3K/Akt pathway

Y Zhang, S Li, X Cui, Y Wang - Apoptosis, 2023 - Springer
Breast cancer is a common malignancy in women with poor prognosis. This study aimed to
investigate the molecular mechanism of microRNA-944 (miR-944) mediated secreted …

microRNA-944 overexpression is a biomarker for poor prognosis of advanced cervical cancer

S Park, J Kim, K Eom, S Oh, S Kim, G Kim, S Ahn… - BMC cancer, 2019 - Springer
Background One-third of cervical cancer patients are still diagnosed at advanced stages.
The five-year survival rate is decreased in about 50% of advanced stage cervical cancer …

Retracted: miR‐944 inhibits metastasis of gastric cancer by preventing the epithelial–mesenchymal transition via MACC1/Met/AKT signaling

T Pan, W Chen, X Yuan, J Shen, C Qin… - FEBS Open bio, 2017 - Wiley Online Library
Micro RNA s (mi RNA s) are reported to play vital roles in tumor progression. Recently, miR‐
944 was reported to play either an oncogenic or tumor suppressive role in human cancers …

PRNCR1: a long non-coding RNA with a pivotal oncogenic role in cancer

A Bardhan, A Banerjee, K Basu, DK Pal, A Ghosh - Human genetics, 2022 - Springer
Long non-coding RNAs (lncRNAs) have been gaining importance in the field of cancer
research in recent years. PRNCR1 (prostate cancer-associated non-coding RNA1) is a 12.7 …