Polyphenols as antitumor agents targeting key players in cancer-driving signaling pathways

MH Cháirez-Ramírez, KG de la Cruz-López… - Frontiers in …, 2021 - frontiersin.org
Polyphenols constitute an important group of natural products that are traditionally
associated with a wide range of bioactivities. These are usually found in low concentrations …

Anti-inflammatory effects of resveratrol: Mechanistic insights

D de Sá Coutinho, MT Pacheco, RL Frozza… - International journal of …, 2018 - mdpi.com
Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside

F Islam, MH Nafady, MR Islam, S Saha, S Rashid… - Molecular …, 2022 - Springer
Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …

Targeting NF-κB signaling pathway in cancer by dietary polyphenols

H Khan, H Ullah, PCMF Castilho… - Critical Reviews in …, 2020 - Taylor & Francis
Being a transcription factor, NF-κB regulates gene expressions involving cell survival and
proliferation, drug resistance, metastasis, and angiogenesis. The activation of NF-κB plays a …

[HTML][HTML] Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial‑mesenchymal transition via the AKT/GSK‑3β/Snail signaling …

L Yuan, M Zhou, D Huang… - Molecular …, 2019 - spandidos-publications.com
The identification of safe and effective drugs that inhibit tumor invasion and metastasis is
required to improve the clinical outcome of patients with colon cancer. The present study …

Targeting oncogenic transcription factors by polyphenols: A novel approach for cancer therapy

C Rajagopal, MB Lankadasari, JM Aranjani… - Pharmacological …, 2018 - Elsevier
Inflammation is one of the major causative factor of cancer and chronic inflammation is
involved in all the major steps of cancer initiation, progression metastasis and drug …

Migration/invasion of malignant gliomas and implications for therapeutic treatment

CA Liu, CY Chang, KW Hsueh, HL Su… - International journal of …, 2018 - mdpi.com
Malignant tumors of the central nervous system (CNS) are among cancers with the poorest
prognosis, indicated by their association with tumors of high-level morbidity and mortality …

Nano-delivery systems for encapsulation of dietary polyphenols: An experimental approach for neurodegenerative diseases and brain tumors

T Squillaro, A Cimini, G Peluso, A Giordano… - Biochemical …, 2018 - Elsevier
Neurodegenerative diseases (NDs) and brain tumors are severe, disabling, and incurable
disorders that represent a critical problem regarding human suffering and the economic …

Unraveling the anticancer effect of curcumin and resveratrol

AR Pavan, GDB Silva, DH Jornada, DE Chiba… - Nutrients, 2016 - mdpi.com
Resveratrol and curcumin are natural products with important therapeutic properties useful
to treat several human diseases, including cancer. In the last years, the number of studies …

Research progress on Alzheimer's disease and resveratrol

Y Yan, H Yang, Y Xie, Y Ding, D Kong, H Yu - Neurochemical research, 2020 - Springer
Abstract Alzheimer's disease (AD), a common irreversible neurodegenerative disease
characterized by amyloid-β plaques, neurofibrillary tangles, and changes in tau …