Recent developments and future prospects of Vitreoscilla hemoglobin application in metabolic engineering

L Zhang, Y Li, Z Wang, Y Xia, W Chen, K Tang - Biotechnology Advances, 2007 - Elsevier
In hypoxic conditions, bacteria express a kind of hemoglobin, which is proposed to enhance
respiration and energy metabolism by promoting oxygen delivery. Bacteria hemoglobin from …

Inhibition of Bacterial Quorum Sensing-Regulated Behaviors by Tremella fuciformis Extract

H Zhu, SJ Sun - Current microbiology, 2008 - Springer
Quorum sensing (QS), or the control of gene expression in response to cell density, is used
by both gram-negative and gram-positive bacteria to regulate a variety of physiological …

Overview of regulatory strategies and molecular elements in metabolic engineering of bacteria

T Wang, X Ma, G Du, J Chen - Molecular biotechnology, 2012 - Springer
From a viewpoint of biotechnology, metabolic engineering mainly aims to change the natural
status of a pathway in a microorganism towards the overproduction of certain bioproducts …

Enhanced production of total flavones and exopolysaccharides via Vitreoscilla hemoglobin biosynthesis in Phellinus igniarius

H Zhu, S Sun, S Zhang - Bioresource technology, 2011 - Elsevier
The Vitreoscilla hemoglobin gene (vgb) was expressed by chromosomal integration in
Phellinus igniarius to alleviate oxygen limitation and improve metabolites yields during …

Applications of the VHb gene vgb for improved microbial fermentation processes

XX Wei, GQ Chen - Methods in enzymology, 2008 - Elsevier
Dissolved oxygen (DO) plays an important role in cell growth, especially in industry-scale
microbial production. To alleviate the defects of hypoxic conditions, Vitreoscilla hemoglobin …

Microbial production of l-glutamate and l-glutamine by recombinant Corynebacterium glutamicum harboring Vitreoscilla hemoglobin gene vgb

Q Liu, J Zhang, XX Wei, SP Ouyang, Q Wu… - Applied microbiology …, 2008 - Springer
Vitreoscilla hemoglobin (VHb) gene vgb equipped with a native promoter Pvgb or a tac
promoter Ptac was introduced into Corynebacterium glutamicum ATCC14067, respectively …

pH-control modes in a 5-L stirred-tank bioreactor for cell biomass and exopolysaccharide production by Tremella fuciformis spore

H Zhu, C Cao, S Zhang, Y Zhang, W Zou - Bioresource technology, 2011 - Elsevier
The effect of pH-control modes on cell growth and exopolysaccharide production by
Tremella fuciformis was evaluated in a 5-L bioreactor. The results show that the maximal dry …

A three-stage culture process for improved exopolysaccharide production by Tremella fuciformis

H Zhu, B Tian, W Liu, S Zhang, C Cao, Y Zhang… - Bioresource …, 2012 - Elsevier
Tremella fuciformis produces several bioactive secondary metabolites including
exopolysaccharides. Cultivation of the fungus was carried out in a three-stage process …

Fungal quorum sensing inhibitors

R Sharma, K Jangid - Quorum sensing vs quorum quenching: a battle with …, 2014 - Springer
Adaptation to various ecosystems is important to all microbes for growth and survival.
Pathogenic microbes, especially bacteria, have developed mechanisms of synchronised …

Constitutive expression of Vitreoscilla haemoglobin in Sphingomonas elodea to improve gellan gum production

XC Wu, YM Chen, YD Li, O Li, L Zhu… - Journal of applied …, 2011 - academic.oup.com
Aims: To improve a commercially used strain for gellan production by exogenous Vitreoscilla
haemoglobin (VHb). Methods and Results: VHb gene was expressed in Sphingomonas …