Cell size varies during the cell cycle and in response to external stimuli. This requires the
tight coordination, or" scaling," of mRNA and protein quantities with the cell volume in order …

The chemical master equation and the Gillespie algorithm are widely used to model the
reaction kinetics inside living cells. It is thereby assumed that cell growth and division can be …

Predicting the evolution of engineered cell populations is a highly sought-after goal in
biotechnology. While models of evolutionary dynamics are far from new, their application to …

Stochastic chemical kinetics is a widely used formalism for studying stochasticity of chemical
reactions inside single cells. Experimental studies of reaction networks are generally …

Predicting the evolution of engineered cell populations is a highly sought-after goal in
biotechnology with the potential to transform our use of genetic devices. While models of …

Glioblastoma (GBM) is the most aggressive malignant primary brain tumour with a median
overall survival of 15 months. To treat GBM, patients currently undergo a surgical resection …

The chemical master equation and the stochastic simulation algorithm are widely used to
model the reaction kinetics inside living cells. It is thereby assumed that cell growth and …