Maternal immune activation (MIA) is strongly associated with an increased risk of developing
mental illness in adulthood, which often co-occurs with alcohol misuse. The current study …

Although most adults in the United States will drink alcohol in their life, only∼ 6% will go on
to develop an alcohol use disorder (AUD). While a great deal of work has furthered our …

Background As alcohol and nicotine use disorders are entwined, it may be possible to
develop a single medication to treat both. We previously developed a model for ethanol …

Rationale The immediate social context significantly influences alcohol consumption in
humans. Recent studies have revealed that peer presence could modulate drugs use in rats …

Background Although male and female rats differ in their patterns of alcohol use, little is
known regarding the neural circuit activity that underlies these differences in behavior. The …

Background Across multiple levels of investigation, there appear to be convergent neuronal
processes underlying substance use and other motivated behaviors (ie, the pursuit and …

Decreased functional connectivity between the striatum and frontal cortex is observed in
individuals with alcohol use disorder (AUD), and predicts the probability of relapse in …

The theoretical framework of this thesis is that schizophrenia and alcohol use disorder may
arise due to the presence of several risk factors in particular epochs in time throughout the …

Rationale: Clinical literature indicates there may be a therapeutic use of cannabidiol (CBD)
for stress-related disorders. Preclinical literature remains conflicted regarding the underlying …

Background While the neurobiology of alcohol use disorder (AUD) has been extensively
researched, the vast majority of these studies included only male organisms. However, there …