Current efforts to optimise subthalamic deep brain stimulation in Parkinson's disease
patients aim to harness local oscillatory activity in the beta frequency range (13–35 Hz) as a …

Subcortical structures are a relative neurophysiological 'terra incognita'owing to their
location within the skull. While perioperative subcortical sensing has been performed for …

Background: Deep brain stimulation (DBS) is a highly efficient, evidence-based therapy to
alleviate symptoms and improve quality of life in movement disorders such as Parkinson's …

Adaptive deep brain stimulation (aDBS) is a promising concept for feedback-based
neurostimulation, with the potential of clinical implementation with the sensing-enabled …

ABSTRACT Background Local field potentials (LFPs) represent the summation of periodic
(oscillations) and aperiodic (fractal) signals. Although previous studies showed changes in …

Background Speech impairment is commonly reported in Parkinson's disease and is not
consistently improved by available therapies–including deep brain stimulation of the …

Objective Bradykinesia is the major cardinal motor sign of Parkinson disease (PD), but its
neural underpinnings are unclear. The goal of this study was to examine whether changes …

Parkinson's disease (PD) is a neurodegenerative disease with a heavy burden on patients,
families, and society. Deep brain stimulation (DBS) can improve the symptoms of PD …

Deep brain stimulation (DBS) offers the unique opportunity to record human neural
population activity as multiunit activity and local field potentials (LFP) directly from the target …

Introduction Deep brain stimulation (DBS) is a life-changing treatment for patients with
Parkinson's disease (PD) and gives the unique opportunity to directly explore how basal …