Quantum sensing

CL Degen, F Reinhard, P Cappellaro - Reviews of modern physics, 2017 - APS
“Quantum sensing” describes the use of a quantum system, quantum properties, or quantum
phenomena to perform a measurement of a physical quantity. Historical examples of …

[HTML][HTML] Challenges and opportunities for large-scale electrophysiology with Neuropixels probes

NA Steinmetz, C Koch, KD Harris… - Current opinion in …, 2018 - Elsevier
Electrophysiological methods are the gold standard in neuroscience because they reveal
the activity of individual neurons at high temporal resolution and in arbitrary brain locations …

Multiregion neuronal activity: the forest and the trees

TA Machado, IV Kauvar, K Deisseroth - Nature Reviews Neuroscience, 2022 - nature.com
The past decade has witnessed remarkable advances in the simultaneous measurement of
neuronal activity across many brain regions, enabling fundamentally new explorations of the …

Scalable tissue labeling and clearing of intact human organs

H Mai, Z Rong, S Zhao, R Cai, H Steinke… - Nature …, 2022 - nature.com
Advances in tissue labeling and clearing methods include improvement of tissue
transparency, better preservation of fluorescence signal, compatibility with immunostaining …

Hydrogel-tissue chemistry: principles and applications

V Gradinaru, J Treweek, K Overton… - Annual review of …, 2018 - annualreviews.org
Over the past five years, a rapidly developing experimental approach has enabled high-
resolution and high-content information retrieval from intact multicellular animal (metazoan) …

MACS: rapid aqueous clearing system for 3D mapping of intact organs

J Zhu, T Yu, Y Li, J Xu, Y Qi, Y Yao, Y Ma… - Advanced …, 2020 - Wiley Online Library
Tissue optical clearing techniques have provided important tools for large‐volume imaging.
Aqueous‐based clearing methods are known for good fluorescence preservation and …

Advancing drug discovery for neurological disorders using iPSC-derived neural organoids

G Costamagna, GP Comi, S Corti - International Journal of Molecular …, 2021 - mdpi.com
In the last decade, different research groups in the academic setting have developed
induced pluripotent stem cell-based protocols to generate three-dimensional, multicellular …

Stimuli-responsive, plasmonic nanogel for dual delivery of curcumin and photothermal therapy for cancer treatment

F Howaili, E Özliseli, B Küçüktürkmen… - Frontiers in …, 2021 - frontiersin.org
Nanogels (Ng) are crosslinked polymer-based hydrogel nanoparticles considered to be next-
generation drug delivery systems due to their superior properties, including high drug …

ERM-dependent assembly of T cell receptor signaling and co-stimulatory molecules on microvilli prior to activation

S Ghosh, V Di Bartolo, L Tubul, E Shimoni… - Cell reports, 2020 - cell.com
T cell surfaces are covered with microvilli, actin-rich and flexible protrusions. We use super-
resolution microscopy to show that≥ 90% of T cell receptor (TCR) complex molecules …

Optical clearing for multiscale biological tissues

T Yu, Y Qi, H Gong, Q Luo, D Zhu - Journal of biophotonics, 2018 - Wiley Online Library
Three‐dimensional reconstruction of tissue structures is essential for biomedical research.
The development of light microscopes and various fluorescent labeling techniques provides …