Pathogenic potential of adipose tissue and metabolic consequences of adipocyte hypertrophy and increased visceral adiposity

HE Bays, JM González-Campoy, GA Bray… - Expert review of …, 2008 - Taylor & Francis
When caloric intake exceeds caloric expenditure, the positive caloric balance and storage of
energy in adipose tissue often causes adipocyte hypertrophy and visceral adipose tissue …

Latent autoimmune diabetes in adults

RG Naik, BM Brooks-Worrell… - The Journal of Clinical …, 2009 - academic.oup.com
Context: Autoantibodies that are reactive to islet antigens are present at the time of
diagnosis in most patients with type 1 diabetes. Additionally, approximately 10% of …

“Sick fat,” metabolic disease, and atherosclerosis

HE Bays - The American journal of medicine, 2009 - Elsevier
Atherosclerotic coronary heart disease (CHD) is the most common cause of morbidity and
mortality among men and women in developed nations. The obesity epidemic contributes to …

Impaired ('diabetic') insulin signaling and action occur in fat cells long before glucose intolerance—is insulin resistance initiated in the adipose tissue?

U Smith - International journal of obesity, 2002 - nature.com
This review postulates and presents recent evidence that insulin resistance is initiated in the
adipose tissue and also suggests that the adipose tissue may play a pivotal role in the …

Risk of cancer following hospitalization for type 2 diabetes

K Hemminki, X Li, J Sundquist, K Sundquist - The Oncologist, 2010 - academic.oup.com
Objectives. Cancer and type 2 diabetes (T2D) are two common diseases that may share risk
factors. We aimed at determining subsequent cancer risks in patients hospitalized for T2D in …

Familial risks for type 2 diabetes in Sweden

K Hemminki, X Li, K Sundquist, J Sundquist - Diabetes care, 2010 - Am Diabetes Assoc
OBJECTIVE Our aim was to characterize familial risks for type 2 diabetes by the type and
number of affected family members, including half-siblings, adoptees, and spouses, to …

Personal understandings of illness among people with type 2 diabetes

Å Hörnsten, H Sandström… - Journal of advanced …, 2004 - Wiley Online Library
Background. Professionals and patients understand the experience of illness from different
worlds. Professionals' explanatory models focus on aetiology, diagnosis, pathophysiology …

Is adiposopathy (sick fat) an endocrine disease?

HE Bays, JM Gonzalez‐Campoy… - … journal of clinical …, 2008 - Wiley Online Library
Objective: To review current consensus and controversy regarding whether obesity is a
'disease', examine the pathogenic potential of adipose tissue to promote metabolic disease …

Association of lipid profile with type 2 diabetes in first-degree relatives: A 14-year follow-up study in Iran

E Sadeghi, SM Hosseini, M Vossoughi… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Purpose Dyslipidemia is claimed to be associated with an increased risk of type 2 diabetes
mellitus (T2DM). However, first-degree relatives (FDRs) of patients with T2DM are reported …

Association between family history risk categories and prevalence of diabetes in Chinese population

J Zhang, Z Yang, J Xiao, X Xing, J Lu, J Weng, W Jia… - PLoS …, 2015 - journals.plos.org
Aim To investigate the association between different family history risk categories and
prevalence of diabetes in the Chinese population. Methods The family history of diabetes …