Heat-killed Lancefieldella rimae induces bone resorption by promoting osteoclast differentiation

J Park, Y Lim, C Park, KY Kum, CH Yun, OJ Park… - Journal of …, 2024 - Elsevier
Introduction Apical periodontitis, mainly caused by bacterial infection in the dental pulp, is
often accompanied by abscess, periapical inflammation, and alveolar bone loss …

Lipoteichoic Acid Rescued Age‐Related Bone Loss by Enhancing Neuroendocrine and Growth Hormone Secretion Through TLR2/COX2/PGE2 Signalling Pathway

Z Liu, Z Lin, Y Chen, M Lu, W Hong… - Journal of Cellular and …, 2024 - Wiley Online Library
The phenomenon of brain–bone crosstalk pertains to the intricate interaction and
communication pathways between the central nervous system and the skeletal system …

D-alanine suppressed osteoclastogenesis derived from bone marrow macrophages and downregulated ERK/p38 signalling pathways

X Chang, J Deng, F Zhou, Z Geng, X Li, S Wang - Archives of Oral Biology, 2024 - Elsevier
Objectives D-alanine is a residue of the backbone structure of Type Ⅰ Lipoteichoic acid
(LTA), which is a virulence factor in inflammation caused by gram-positive bacteria …

[HTML][HTML] α-IRAK-4 Suppresses the Activation of RANK/RANKL Pathway on Macrophages Exposed to Endodontic Microorganisms

EM Hernández-Sandoval, R Sánchez-Gutiérrez… - International Journal of …, 2024 - mdpi.com
Periapical lesions are common pathologies affecting the alveolar bone, often initiated by
intraradicular lesions resulting from microbial exposure to dental pulp. These …