Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …

Alveolarization is the process by which the alveoli, the principal gas exchange units of the
lung, are formed. Along with the maturation of the pulmonary vasculature, alveolarization is …

Heat-not-burn (HNB) devices can alter vital physiological functions in the lung. HNB devices
may not be a safer option than cigarette smoking or eCig vaping; this does not support the …

Respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), lung
fibrosis, and lung cancer, pose a huge socio-economic burden on society and are one of the …

Airway structure and function are key aspects of normal lung development, growth, and
aging, as well as of lung responses to the environment and the pathophysiology of important …

Chronic obstructive pulmonary disease (COPD) is a debilitating respiratory disease and one
of the leading causes of morbidity and mortality worldwide. It is characterized by persistent …

Supplemental O2 (hyperoxia; 30–90% O2) is a necessary intervention for premature infants,
but it contributes to development of neonatal and pediatric asthma, necessitating better …

Pulmonary fibrosis is a devastating disease characterized by accumulation of activated
fibroblasts and scarring in the lung. While fibroblast activation in physiological wound repair …

Hyperoxia exposure in premature infants increases the risk of subsequent lung diseases,
such as asthma and bronchopulmonary dysplasia. Fibroblasts help maintain bronchial and …

Myofibroblasts play key roles in wound healing and pathological fibrosis. Here, we used an
RNAi screen to characterize myofibroblast regulatory genes, using a high-content imaging …