Emergence and spread of resistance in Plasmodium falciparum to the frontline treatment
artemisinin-based combination therapies (ACTs) in the epicenter of multidrug resistance of …

China has now achieved the elimination of malaria, but it still faces severe challenges in the
post-elimination stage. China continues to be plagued by imported malaria cases, and …

Multidrug-resistant Plasmodium falciparum parasites have emerged in Cambodia and
neighboring countries in Southeast Asia, compromising the efficacy of first-line antimalarial …

In the course of malaria elimination in the Greater Mekong Subregion (GMS), malaria
epidemiology has experienced drastic spatiotemporal changes with residual transmission …

The malaria landscape in the Greater Mekong Subregion has experienced drastic changes
with the ramp-up of the control efforts, revealing formidable challenges that slowed down the …

Background The fast-declining clinical efficacy of dihydroartemisinin-piperaquine (DHA-
PPQ) in Cambodia is a warning of the underlying westward dissemination of piperaquine …

Malaria remains a major public health concern. The rapid spread of resistance to
antimalarial drugs is a major challenge for malaria eradication. Timely and accurate …

The Greater Mekong Subregion (GMS) is the epicenter of antimalarial drug resistance. We
determined in vitro susceptibilities to 11 drugs of culture-adapted Plasmodium falciparum …

The emergence and spread of drug-resistant Plasmodium falciparum have compromised
antimalarial efficacy and threatened the global malaria elimination campaign using …

Abstract Background The rise in Plasmodium falciparum resistance to dihydroartemisinin–
piperaquine (DHA–PPQ) treatment has been documented in the Greater Mekong Subregion …