This paper presents an overview of methods that have been proposed for the analysis of
breast cancer histopathology images. This research area has become particularly relevant …

Simple Summary The breakthrough in developing novel HER2-targeting antibody drug
conjugates and identifying their clinical benefits in HER2-low breast cancer will dramatically …

Abstract Immunohistochemical (IHC) assays performed on formalin-fixed paraffin-embedded
(FFPE) tissue sections traditionally have been semi-quantified by pathologist visual scoring …

In the spectrum of breast cancers, categorization according to the four gene expression-
based subtypes 'Luminal A,''Luminal B,''HER2-enriched,'and 'Basal-like'is the method of …

Breast cancer represents a heterogeneous group of human cancer at both histological and
molecular levels. Estrogen receptor (ER), progesterone receptor (PR) and human epidermal …

The new human epidermal growth factor receptor (HER) 2-targeting antibody-drug
conjugate offers the opportunity to treat patients with HER2-low breast cancer …

Context.—Increasing implementation of whole slide imaging together with digital workflow
and advances in computing capacity enable the use of artificial intelligence (AI) in …

Tissue biomarkers have been of increasing utility for scientific research, diagnosing disease,
and treatment response prediction. There has been a steady shift away from qualitative …

Advancements in technology and digitization have ushered in novel ways of enhancing
tissue-based research via digital microscopy and image analysis. Whole slide imaging …

Astrocytomas are the most frequent primary brain tumors in adults, and despite aggressive
treatment patients often experience recurrence. Survival decreases with increasing tumor …