Tuberculosis (TB) lesions are extremely complex and dynamic. Here, we review the multiple
types and fates of pulmonary lesions that form following infection by M ycobacterium …

The different manifestations of infection with Mycobacterium tuberculosis reflect the balance
between the bacillus and host defense mechanisms. Traditionally, protective immunity to …

Neutrophils are rapidly recruited to sites of mycobacterial infection, where they phagocytose
bacilli. Whether neutrophils can kill mycobacteria in vivo probably depends on the tissue …

Mycobacteria are endowed with mechanisms through which they can evade the onslaught
of host defense response. These mechanisms are discussed including diminishing the …

Mycobacterium tuberculosis is one of the most ubiquitous pathogens in the world: estimates
are that roughly one third of the world's population is infected with the bacillus, and it is …

Pulmonary cavities, the hallmark of tuberculosis (TB), are characterized by high
mycobacterial load and perpetuate the spread of M. tuberculosis. The mechanism of matrix …

Protective immunity against pulmonary tuberculosis (TB) is characterized by the formation in
the lungs of granulomas consisting of macrophages and activated T cells producing tumor …

Heterologous prime-boost immunization strategies can evoke powerful T cell immune
responses and may be of value in developing an improved tuberculosis vaccine. We show …

Tuberculosis is a global public health catastrophe responsible for> 8 million cases of illness
and 2 million deaths annually. Pulmonary cavitation with cough-generated aerosol is the …

Tuberculosis is the most important bacterial infection world wide. The causative agent,
Mycobacterium tuberculosis survives and proliferates within macrophages. Immune …