Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup
CR Jack Jr, JS Andrews, TG Beach… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract The National Institute on Aging and the Alzheimer's Association convened three
separate work groups in 2011 and single work groups in 2012 and 2018 to create …
separate work groups in 2011 and single work groups in 2012 and 2018 to create …
APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease
This study aimed to evaluate the impact of APOE4 homozygosity on Alzheimer's disease
(AD) by examining its clinical, pathological and biomarker changes to see whether APOE4 …
(AD) by examining its clinical, pathological and biomarker changes to see whether APOE4 …
Clinical and research application of fluid biomarkers in autosomal dominant Alzheimer's disease and Down syndrome
Autosomal dominant Alzheimer's disease (ADAD) and Down syndrome (DS) constitute
genetic forms of Alzheimer's disease (AD). The study of these forms has been crucial in …
genetic forms of Alzheimer's disease (AD). The study of these forms has been crucial in …
Going beyond established model systems of Alzheimer's disease: companion animals provide novel insights into the neurobiology of aging
AA de Sousa, BA Rigby Dames, EC Graff… - Communications …, 2023 - nature.com
Alzheimer's disease (AD) is characterized by brain plaques, tangles, and cognitive
impairment. AD is one of the most common age-related dementias in humans. Progress in …
impairment. AD is one of the most common age-related dementias in humans. Progress in …
AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease
Objective We develop a deep learning framework based on the pre-trained Bidirectional
Encoder Representations from Transformers (BERT) model using unstructured clinical notes …
Encoder Representations from Transformers (BERT) model using unstructured clinical notes …
Reply to: Challenges to identifying risk versus protective factors in Alzheimer's disease
Pappalettera et al. 1 raise important points concerning our recent publication on APOE4
homozygotes 2, specifically about the definition of Alzheimer's disease (AD), resilience …
homozygotes 2, specifically about the definition of Alzheimer's disease (AD), resilience …
Plasma and cerebrospinal fluid glial fibrillary acidic protein levels in adults with Down syndrome: a longitudinal cohort study
Background The diagnosis of symptomatic Alzheimer's disease is a clinical challenge in
adults with Down syndrome. Blood biomarkers would be of particular clinical importance in …
adults with Down syndrome. Blood biomarkers would be of particular clinical importance in …
Lecanemab and vascular-amyloid deposition in brains of people with Down syndrome
L Liu, A Saba, JR Pascual, MB Miller… - JAMA …, 2024 - jamanetwork.com
Importance Anti-β-amyloid immunotherapy using lecanemab is becoming increasingly
available to patients with Alzheimer disease (AD). Individuals with Down syndrome (DS) …
available to patients with Alzheimer disease (AD). Individuals with Down syndrome (DS) …
Longitudinal clinical and cognitive changes along the Alzheimer disease continuum in Down syndrome
L Videla, B Benejam, J Pegueroles… - JAMA network …, 2022 - jamanetwork.com
Importance Alzheimer disease (AD) is the main medical problem in adults with Down
syndrome (DS). However, the associations of age, intellectual disability (ID), and clinical …
syndrome (DS). However, the associations of age, intellectual disability (ID), and clinical …
Down syndrome in a new era for Alzheimer disease
US Food and Drug Administration–approveddisease-modifyingtreatmentsforAlzheimerdiseasear…
by prescription. This recent approval is based on evidence from large randomized, placebo …
by prescription. This recent approval is based on evidence from large randomized, placebo …