Recent advances in miRNA delivery systems

I Dasgupta, A Chatterjee - Methods and protocols, 2021 - mdpi.com
MicroRNAs (miRNAs) represent a family of short non-coding regulatory RNA molecules that
are produced in a tissue and time-specific manner to orchestrate gene expression post …

Melodic maestros: Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of malignant pleural mesothelioma

MA Abd-Elmawla, SSA Mageed… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly lethal form of pleural cancer
characterized by a scarcity of effective therapeutic interventions, resulting in unfavorable …

Integrative molecular characterization of malignant pleural mesothelioma

J Hmeljak, F Sanchez-Vega, KA Hoadley, J Shih… - Cancer discovery, 2018 - AACR
Malignant pleural mesothelioma (MPM) is a highly lethal cancer of the lining of the chest
cavity. To expand our understanding of MPM, we conducted a comprehensive integrated …

MicroRNAs in cancer cell death pathways: Apoptosis and necroptosis

S Shirjang, B Mansoori, S Asghari, PHG Duijf… - Free Radical Biology …, 2019 - Elsevier
To protect tissues and the organism from disease, potentially harmful cells are removed
through programmed cell death processes, including apoptosis and necroptosis. These …

Emerging genotype–phenotype relationships in patients with large NF1 deletions

H Kehrer-Sawatzki, VF Mautner, DN Cooper - Human Genetics, 2017 - Springer
The most frequent recurring mutations in neurofibromatosis type 1 (NF1) are large deletions
encompassing the NF1 gene and its flanking regions (NF1 microdeletions). The majority of …

Clinical development of TargomiRs, a miRNA mimic-based treatment for patients with recurrent thoracic cancer

G Reid, SC Kao, N Pavlakis, H Brahmbhatt… - …, 2016 - Taylor & Francis
miRNAs are responsible for post-transcriptional control of gene expression, and are
frequently downregulated in cancer. It has become well established that restoring miRNA …

Deciphering signaling pathway interplay via miRNAs in malignant pleural mesothelioma

A Salman, SSA Mageed, D Fathi, MA Elrebehy… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly invasive form of lung cancer that
adversely affects the pleural and other linings of the lungs. MPM is a very aggressive tumor …

[HTML][HTML] Tumor suppressor microRNAs contribute to the regulation of PD-L1 expression in malignant pleural mesothelioma

SC Kao, YY Cheng, M Williams, MB Kirschner… - Journal of Thoracic …, 2017 - Elsevier
Introduction The upregulation of programmed death ligand 1 (PD-L1) is found in many
cancers and contributes to evasion of the host's immune defense. In malignant pleural …

Therapeutic advancements in targeting BCL-2 family proteins by epigenetic regulators, natural, and synthetic agents in cancer

A Sarkar, A Paul, T Banerjee, A Maji, S Saha… - European Journal of …, 2023 - Elsevier
Cancer is amongst the deadliest and most disruptive disorders, having a much higher death
rate than other diseases worldwide. Human cancer rates continue to rise, thereby posing the …

miR‐193: a new weapon against cancer

M Khordadmehr, R Shahbazi… - Journal of cellular …, 2019 - Wiley Online Library
Abstract microRNAs (miRNAs) are known as a large group of short noncoding RNAs, which
structurally consist of 19–22 nucleotides in length and functionally act as one of the main …