Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases

LA Adams, QM Anstee, H Tilg, G Targher - Gut, 2017 - gut.bmj.com
Key physiological functions of the liver, including glucose and lipid metabolism, become
disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be associated …

Arterial stiffness, atherosclerosis and cardiovascular risk: Pathophysiologic mechanisms and emerging clinical indications

C Palombo, M Kozakova - Vascular pharmacology, 2016 - Elsevier
Arterial stiffness results from a degenerative process affecting mainly the extracellular matrix
of elastic arteries under the effect of aging and risk factors. Changes in extracellular matrix …

AASLD Practice Guideline on imaging-based noninvasive liver disease assessment of hepatic fibrosis and steatosis

RK Sterling, A Duarte-Rojo, K Patel, SK Asrani… - Hepatology, 2025 - journals.lww.com
Chronic liver disease (CLD) is associated with approximately two million annual deaths
worldwide and is an enormous health burden.[1, 2] The majority of liver-related outcomes …

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

QM Anstee, G Targher, CP Day - Nature reviews Gastroenterology & …, 2013 - nature.com
NAFLD is a spectrum of progressive liver disease that encompasses simple steatosis,
NASH, fibrosis and, ultimately, cirrhosis. NAFLD is recognized as the hepatic component of …

Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease

M Gaggini, M Morelli, E Buzzigoli, RA DeFronzo… - Nutrients, 2013 - mdpi.com
Non-alcoholic fatty liver disease is marked by hepatic fat accumulation not due to alcohol
abuse. Several studies have demonstrated that NAFLD is associated with insulin resistance …

Nonalcoholic fatty liver disease pandemic fuels the upsurge in cardiovascular diseases

J Cai, XJ Zhang, YX Ji, P Zhang, ZG She… - Circulation research, 2020 - Am Heart Assoc
Cardiovascular diseases (CVDs) remain a leading cause of death worldwide. Among the
major risk factors for CVD, obesity and diabetes mellitus have received considerable …

[HTML][HTML] From NAFLD in clinical practice to answers from guidelines

F Nascimbeni, R Pais, S Bellentani, CP Day… - Journal of …, 2013 - Elsevier
This review of the literature consists of three sections. First, papers concerning non-alcoholic
fatty liver disease (NAFLD) awareness among the general population, general practitioners …

Localization of fat depots and cardiovascular risk

O Gruzdeva, D Borodkina, E Uchasova… - Lipids in health and …, 2018 - Springer
Despite the existing preventative and therapeutic measures, cardiovascular diseases
remain the main cause of temporary disability, long-term disability, and mortality. Obesity is a …

Gamma-glutamyl transferase and the risk of atherosclerosis and coronary heart disease

G Ndrepepa, R Colleran, A Kastrati - Clinica chimica acta, 2018 - Elsevier
Gamma-glutamyl transferase (GGT) is a ubiquitous cell surface enzyme that cleaves
extracellular glutathione (G-SH) or other gamma-glutamyl compounds. GGT serves to …

the diagnosis of non‐alcoholic fatty liver disease–availability and accuracy of non‐invasive methods

D Festi, R Schiumerini, L Marzi… - Alimentary …, 2013 - Wiley Online Library
Background Non‐alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of
clinical conditions, actually representing an emerging disease of great clinical interest …