New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …

Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …

Introduction microRNA (miRNA) are small non-coding RNA species that are transcriptionally
processed in the host cell and released extracellularly into the bloodstream. Normally …

There is no consensus for a blood-based test for the early diagnosis of Alzheimer's disease
(AD). Expression profiling of small non-coding RNA's, microRNA (miRNA), has revealed …

Analyzing microRNAs (miRNAs) within urine extracellular vesicles (EVs) is important for
realizing miRNA-based, simple, and noninvasive early disease diagnoses and timely …

In the last years, circulating miRNAs have emerged as a new class of promising cancer
biomarkers. Independent studies have shown the feasibility of using these small RNAs as …

Immunotherapies have emerged as one of the most promising approaches to treat patients
with cancer. Recently, there have been many clinical successes using checkpoint receptor …

Background MicroRNAs have been identified as potential cancer biomarkers due to their
presence and stability in many body fluids including urine and plasma, but the relationship …

Hemolysis is a pathological feature of several diseases of diverse etiology such as
hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the …

Exosomes are nano-vesicles present in the circulation that are involved in cell-to-cell
communication and regulation of different biological processes. MicroRNAs (miRNAs) are …