S Liberski, M Wichrowska, J Kocięcki - International Journal of Molecular …, 2022 - mdpi.com
Diabetic macular edema (DME) and neovascular age-related macular degeneration (nAMD) are common retinal vascular diseases responsible for most blindness in the working-age …
A Pugazhendhi, M Hubbell, P Jairam… - International Journal of …, 2021 - mdpi.com
Neovascular age-related macular degeneration (exudative or wet AMD) is a prevalent, progressive retinal degenerative macular disease that is characterized by …
X Wang, T Wang, E Lam, D Alvarez, Y Sun - International Journal of …, 2023 - mdpi.com
The eye is an immune privileged tissue that insulates the visual system from local and systemic immune provocation to preserve homeostatic functions of highly specialized retinal …
NJY Yeo, EJJ Chan, C Cheung - Frontiers in Pharmacology, 2019 - frontiersin.org
Many conditions affecting the heart, brain, and even the eyes have their origins in blood vessel pathology, underscoring the role of vascular regulation. In age-related macular …
AR Fernandes, A Zielińska, E Sanchez-Lopez… - International journal of …, 2022 - mdpi.com
Age-related macular degeneration (AMD) is an eye disease typically associated with the aging and can be classified into two types—namely, the exudative and the nonexudative …
AM Khanani, MW Russell, AA Aziz… - Clinical …, 2021 - Taylor & Francis
Abstract The Ang/Tie2 pathway complements VEGF-mediated activity in retinal vascular diseases such as DME, AMD, and RVO by decreasing vascular integrity, increasing …
N Terao, H Koizumi, K Kojima, T Yamagishi… - Scientific Reports, 2018 - nature.com
This study investigated the pathophysiological features of pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD) by analysing and …
While the development of anti-vascular endothelial growth factor (anti-VEGF) as a therapy for neovascular age-related macular degeneration (AMD) was a great success, the …
Anti-angiogenic approaches have significantly advanced the treatment of vascular-related pathologies. The ephemeral outcome and known side effects of the current vascular …