[HTML][HTML] The role of inflammation in age-related macular degeneration

W Tan, J Zou, S Yoshida, B Jiang… - International journal of …, 2020 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD) is a blinding eye disease which incidence
gradually increases with age. Inflammation participates in AMD pathogenesis, including …

Aflibercept versus faricimab in the treatment of neovascular age-related macular degeneration and diabetic macular edema: a review

S Liberski, M Wichrowska, J Kocięcki - International Journal of Molecular …, 2022 - mdpi.com
Diabetic macular edema (DME) and neovascular age-related macular degeneration (nAMD)
are common retinal vascular diseases responsible for most blindness in the working-age …

Neovascular macular degeneration: a review of etiology, risk factors, and recent advances in research and therapy

A Pugazhendhi, M Hubbell, P Jairam… - International Journal of …, 2021 - mdpi.com
Neovascular age-related macular degeneration (exudative or wet AMD) is a prevalent,
progressive retinal degenerative macular disease that is characterized by …

Ocular vascular diseases: from retinal immune privilege to inflammation

X Wang, T Wang, E Lam, D Alvarez, Y Sun - International Journal of …, 2023 - mdpi.com
The eye is an immune privileged tissue that insulates the visual system from local and
systemic immune provocation to preserve homeostatic functions of highly specialized retinal …

Choroidal neovascularization: mechanisms of endothelial dysfunction

NJY Yeo, EJJ Chan, C Cheung - Frontiers in Pharmacology, 2019 - frontiersin.org
Many conditions affecting the heart, brain, and even the eyes have their origins in blood
vessel pathology, underscoring the role of vascular regulation. In age-related macular …

Exudative versus nonexudative age-related macular degeneration: physiopathology and treatment options

AR Fernandes, A Zielińska, E Sanchez-Lopez… - International journal of …, 2022 - mdpi.com
Age-related macular degeneration (AMD) is an eye disease typically associated with the
aging and can be classified into two types—namely, the exudative and the nonexudative …

Angiopoietins as potential targets in management of retinal disease

AM Khanani, MW Russell, AA Aziz… - Clinical …, 2021 - Taylor & Francis
Abstract The Ang/Tie2 pathway complements VEGF-mediated activity in retinal vascular
diseases such as DME, AMD, and RVO by decreasing vascular integrity, increasing …

Distinct aqueous humour cytokine profiles of patients with pachychoroid neovasculopathy and neovascular age-related macular degeneration

N Terao, H Koizumi, K Kojima, T Yamagishi… - Scientific Reports, 2018 - nature.com
This study investigated the pathophysiological features of pachychoroid neovasculopathy
(PNV) and neovascular age-related macular degeneration (nAMD) by analysing and …

[HTML][HTML] Advances in age-related macular degeneration understanding and therapy

JW Miller, S Bagheri, DG Vavvas - US ophthalmic review, 2017 - ncbi.nlm.nih.gov
While the development of anti-vascular endothelial growth factor (anti-VEGF) as a therapy
for neovascular age-related macular degeneration (AMD) was a great success, the …

Targeting the angiopoietin/tie pathway: prospects for treatment of retinal and respiratory disorders

RG Akwii, CM Mikelis - Drugs, 2021 - Springer
Anti-angiogenic approaches have significantly advanced the treatment of vascular-related
pathologies. The ephemeral outcome and known side effects of the current vascular …