Chitosan scaffolds: Expanding horizons in biomedical applications

AD Gholap, S Rojekar, HS Kapare… - Carbohydrate …, 2024 - Elsevier
Chitosan, a natural polysaccharide from chitin, shows promise as a biomaterial for various
biomedical applications due to its biocompatibility, biodegradability, antibacterial activity …

Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine Drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

Mucosal vaccines: Strategies and challenges

M Li, Y Wang, Y Sun, H Cui, SJ Zhu, HJ Qiu - Immunology letters, 2020 - Elsevier
Mucosal immunization has potential benefits over conventional parenteral immunization,
eliciting immune defense in both mucosal and systemic tissue for protecting from pathogen …

Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity

G Liu, M Zhu, X Zhao, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
After centuries of development, using vaccination to stimulate immunity has become an
effective method for prevention and treatment of a variety of diseases including infective …

Biopharmaceutical applications of microbial polysaccharides as materials: a review

Y Song, S Li, H Gong, RCS Yip, H Chen - International Journal of Biological …, 2023 - Elsevier
Biological characteristics of natural polymers make microbial polysaccharides an excellent
choice for biopharmaceuticals. Due to its easy purifying procedure and high production …

Chitosan-based nanomaterial as immune adjuvant and delivery carrier for vaccines

X Gong, Y Gao, J Shu, C Zhang, K Zhao - Vaccines, 2022 - mdpi.com
With the support of modern biotechnology, vaccine technology continues to iterate. The
safety and efficacy of vaccines are some of the most important areas of development in the …

Chitosan mediated solid lipid nanoparticles for enhanced liver delivery of zedoary turmeric oil in vivo

B Yang, J Jiang, L Jiang, P Zheng, F Wang… - International journal of …, 2020 - Elsevier
Zedoary turmeric oil (ZTO) has a strong antitumor activity. However, its volatility, insolubility,
low bioavailability, and difficulty of medication owing to oily liquid limit its clinical …

Polymer-based nanosystems—A versatile delivery approach

AG Niculescu, AM Grumezescu - Materials, 2021 - mdpi.com
Polymer-based nanoparticles of tailored size, morphology, and surface properties have
attracted increasing attention as carriers for drugs, biomolecules, and genes. By protecting …

Research and Application of Chitosan Nanoparticles in Orthopedic Infections

S Shi, W Shi, B Zhou, S Qiu - International Journal of …, 2024 - Taylor & Francis
Orthopedic infection is one of the most intractable orthopedic problems. Bacteria resistant to
antibiotics also develop gradually. Chitosan is widely used in the Biomedical field because …

Immune enhancement of N-2-Hydroxypropyl trimethyl ammonium chloride chitosan/carboxymethyl chitosan nanoparticles vaccine

Y Gao, X Gong, S Yu, Z Jin, Q Ruan, C Zhang… - International Journal of …, 2022 - Elsevier
The immunogenicity and toxicity of N-2-Hydroxypropyl trimethyl ammonium chloride
chitosan/N, O-carboxymethyl chitosan nanoparticles (N-2-HACC/CMCS NPs) as a universal …