Thromboprophylaxis with argatroban in critically ill patients with sepsis: a review

M Bachler, LM Asmis, J Koscielny, T Lang… - Blood Coagulation & …, 2022 - journals.lww.com
During sepsis, an initial prothrombotic shift takes place, in which coagulatory acute-phase
proteins are increased, while anticoagulatory factors and platelet count decrease. Further …

Influence of factor XII deficiency on activated partial thromboplastin time (aPTT) in critically ill patients

M Bachler, C Niederwanger, T Hell, J Höfer… - Journal of thrombosis …, 2019 - Springer
FXII deficiency results in spontaneous prolongation of activated partial thromboplastin time
(aPTT), which is widely used to monitor thromboprophylaxis. Misinterpretation of …

A statistically rigorous deep neural network approach to predict mortality in trauma patients admitted to the intensive care unit

FS Ahmed, L Ali, BA Joseph, A Ikram… - Journal of Trauma …, 2020 - journals.lww.com
BACKGROUND Trauma patients admitted to critical care are at high risk of mortality
because of their injuries. Our aim was to develop a machine learning-based model to predict …

Coagulative biomarkers on admission to the ICU predict acute kidney injury and mortality in patients with septic shock caused by intra-abdominal infection

Z Xu, B Cheng, S Fu, X Liu, G Xie, Z Li, Y Ji… - Infection and Drug …, 2019 - Taylor & Francis
Purpose Sepsis-associated coagulopathy (SAC) contributes to the development of multiple
organ failure (MOF) and increasing mortality. The present study was conducted to …

Prognostic value of sepsis-induced coagulation abnormalities: an early assessment in the emergency department

F Innocenti, AM Gori, B Giusti, C Tozzi… - Internal and Emergency …, 2019 - Springer
To evaluate if the assessment of coagulation abnormalities at ED admission could improve
prognostic assessment of septic patients. This report utilizes a portion of the data collected in …

Early predicting 30-day mortality in sepsis in MIMIC-III by an artificial neural networks model

Y Su, C Guo, S Zhou, C Li, N Ding - European Journal of Medical …, 2022 - Springer
Objective Early identifying sepsis patients who had higher risk of poor prognosis was
extremely important. The aim of this study was to develop an artificial neural networks (ANN) …

The association of coagulation indicators with in-hospital mortality and 1-year mortality of patients with sepsis at ICU admissions: a retrospective cohort study

R Zheng, H Pan, JF Wang, XS Yu, ZQ Chen, JY Pan - Clinica Chimica Acta, 2020 - Elsevier
Background Coagulation activation is the host's response to pathogens during sepsis and is
considered to be one of the reasons for tissue damage and multiple organ failure. This study …

Protective effect of pregabalin on renal and renal endothelial damage in sepsis induced by lipopolysaccharide

D Çevik, N Gümral, R Aslankoç, Ö Özmen… - …, 2024 - Taylor & Francis
Objective We investigated the protective effects of pregabalin (PRG) on kidney and renal
endothelial damage in sepsis induced by Lipopolysaccharide (LPS). Materials and Methods …

Developing an early warning system for detecting sepsis in patients with trauma

K Guo, B Pan, X Zhang, D Hu, G Xu… - International Wound …, 2024 - Wiley Online Library
The purpose of this study was to analyse the risk factors for sepsis in patients with trauma
and develop a new scoring system for predicting sepsis in patients with trauma based on …

Intravenous vitamin K1 for the correction of prolonged prothrombin times in non-bleeding critically ill patients: a prospective observational study

S Dahlberg, U Schött, EÄ Eriksson, Y Tahirsylaj… - Nutrients, 2021 - mdpi.com
The aim of this study was to evaluate the effects of vitamin K1 on various vitamin K-
dependent proteins in critically ill patients with prolonged Owren PT. We included critically ill …