Atrophy is a classical hallmark of an array of disorders that affect skeletal muscle, ranging
from inherited dystrophies, acquired inflammatory myopathies, ageing (sarcopenia) and …

In recent years, the interest in oxygen–ozone (O2O3) therapy application has considerably
increased in the field of rehabilitation. Despite its widespread use in common clinical …

The conventional forelimb grip strength test is a widely used method to assess skeletal
muscle function in rodents; in this study, we modified this method to improve its variability …

The immune response to acute muscle damage is important for normal repair. However, in
chronic diseases such as many muscular dystrophies, the immune response can amplify …

Skeletal muscle atrophy is a common complication in survivors of sepsis, which affects the
respiratory and motor functions of patients, thus severely impacting their quality of life and …

Peroxisome proliferator-activated receptor γ (PPARγ) is a transcriptional coactivator that
binds to a diverse range of transcription factors. PPARγ coactivator 1 (PGC-1) coactivators …

Muscle development, growth, and maintenance require an intricate and timely series of
events initiated through a multitude of signaling pathways. The very nature of skeletal …

Duchenne muscular dystrophy (DMD) is a fatal X-chromosome linked recessive disorder
caused by the truncation or deletion of the dystrophin gene. The most widely used animal …

Oxidative stress is a loss of balance between the production of reactive oxygen species
during cellular metabolism and the mechanisms that clear these species to maintain cellular …

Imbalances in redox homeostasis can result in oxidative stress, which is implicated in
various pathological conditions including the fatal neuromuscular disease Duchenne …