Brønsted acid-promoted synthesis of common heterocycles and related bio-active and functional molecules

S Ponra, KC Majumdar - RSC advances, 2016 - pubs.rsc.org
Various heterocyclic systems based on natural and unnatural biologically active products
were synthesized by Brønsted acid-promoted cyclization. We have made an attempt to …

Catalyst-Free Synthesis of Pyrrolo[1,2-a]quinolines via Dehydration/[3 + 2] Cycloaddition Directly from 2-Methylquinolines, Aldehydes, and Alkynoates

F Wu, H Zhao, Y Xu, K Hu, Y Pan… - The Journal of Organic …, 2017 - ACS Publications
A simple and efficient catalyst-free synthesis of pyrrolo [1, 2-a] quinoline derivatives from 2-
methylquinolines, aldehydes, and alkynoates via dehydration/[3+ 2] cycloaddition has been …

New atropoisomeric alkenylphenylglycine derivatives: Synthesis of (5R*)-and (5S*)-isomers of (1R*, 3aR*, 4S*, 11S*)-3a, 5, 9, 11-tetramethyl-4, 5-dihydro-3aH-1, 4 …

GG Bizhanova, KY Suponitsky, YV Vakhitova… - Tetrahedron, 2017 - Elsevier
We synthesized methyl ester of N-(1-methylbut-2-en-1-yl)-N-phenylglycine which underwent
acid catalyzed aromatic amino Claisen rearrangement to provide methyl-N-[2-(1-methylbut-2 …

[HTML][HTML] Synthesis and toxicity evaluation of new pyrroles obtained by the reaction of activated alkynes with 1-methyl-3-(Cyanomethyl) benzimidazolium bromide

BC Ivan, F Dumitrascu, AI Anghel, RV Ancuceanu… - Molecules, 2021 - mdpi.com
A series of new pyrrole derivatives were designed as chemical analogs of the 1, 4-
dihydropyridines drugs in order to develop future new calcium channel blockers. The new tri …

Catalyst-Free Synthesis of 1, 4-Dihydroquinolines and Pyrrolo [1, 2-a] quinolines via Intermolecular [4+ 2]/[3+ 2] Radical Cyclization of N-Methylanilines with …

Z Luo, X Han, C Liu, Q Liu, R Li, P Liu, X Xu - Synthesis, 2020 - thieme-connect.com
Intermolecular [4+ 2]/[3+ 2] radical annulation of N-methylanilines with alkynoates under
metal-and photoredox-catalyst-free conditions provides a practical and efficient method to …

A versatile synthesis of cyclic dipeptides using the stepwise construction of the piperazine-2, 5-dione ring from simple precursors: synthetic sequence and the structure …

LM Acosta Quintero, A Palma, J Cobo… - … Section C: Structural …, 2018 - journals.iucr.org
A versatile synthesis of multiply substituted cyclic dipeptides has been designed, based on
the stepwise construction of the piperazine-2, 5-dione ring using molecular fragments from …

Unexpected ring-closure products derived from 3-(2-allylanilino)-3-phenylacrylate esters: crystal and molecular structures of 3-acetyl-8-allyl-6-methyl-2-phenylquinolin …

AL Luque, CM Sanabria, A Palma, J Cobo… - … Section C: Structural …, 2016 - journals.iucr.org
The reactions of two 3-(2-allylanilino)-3-phenylacrylate esters with acetic anhydride and with
strong acids has revealed a richly diverse reactivity providing a number of unexpected …