Metagenomic applications in microbial diversity, bioremediation, pollution monitoring, enzyme and drug discovery. A review

S Datta, KN Rajnish, MS Samuel… - Environmental …, 2020 - Springer
Metagenomics is a technology employed to study genetic material directly isolated from
environmental samples. Metagenomics thus reveals knowledge on microbial communities of …

Metagenome analysis: a powerful tool for enzyme bioprospecting

A Madhavan, R Sindhu, B Parameswaran… - Applied biochemistry …, 2017 - Springer
Microorganisms are found throughout every corner of nature, and vast number of
microorganisms is difficult to cultivate by classical microbiological techniques. The advent of …

Antibiofilm Activity of α-Amylase from Bacillus subtilis and Prediction of the Optimized Conditions for Biofilm Removal by Response Surface Methodology (RSM) and …

D Lahiri, M Nag, T Sarkar, B Dutta, RR Ray - Applied Biochemistry and …, 2021 - Springer
Abstract α-amylase is known to have antibiofilm activity against biofilms of both Gram
positive and Gram-negative bacterial strains. Partially purified α-amylase from Bacillus …

Amylases from thermophilic bacteria: structure and function relationship

BA Kikani, SP Singh - Critical Reviews in Biotechnology, 2022 - Taylor & Francis
Amylases hydrolyze starch to diverse products including dextrins and progressively smaller
polymers of glucose units. Thermally stable amylases account for nearly 25% of the enzyme …

Microbial Amylase: Old but still at the forefront of all major industrial enzymes

S Mondal, K Mondal, SK Halder, N Thakur… - Biocatalysis and …, 2022 - Elsevier
Global climate change builds colossal pressure on humans for sustainable development,
leading to our dependence on enzymes to replace chemicals in several industrial fields …

Challenges and prospects of microbial α-amylases for industrial application: A review

PP Ashok, D Dasgupta, A Ray, SK Suman - World Journal of Microbiology …, 2024 - Springer
Abstract α-Amylases are essential biocatalysts representing a billion-dollar market with
significant long-term global demand. They have varied applications ranging from detergent …

Hunt for α-amylase from metagenome and strategies to improve its thermostability: a systematic review

P Sharma, K Mondal, KC Mondal, N Thakur - World Journal of …, 2022 - Springer
With the advent of green chemistry, the use of enzymes in industrial processes serves as an
alternative to the conventional chemical catalysts. A high demand for sustainable processes …

Isolation and characterization of a cold-active, alkaline, detergent stable α-amylase from a novel bacterium Bacillus subtilis N8

N Arabacı, B Arıkan - Preparative Biochemistry and Biotechnology, 2018 - Taylor & Francis
ABSTRACT A cold-active alkaline amylase producer Bacillus subtilis N8 was isolated from
soil samples. Amylase synthesis optimally occurred at 15° C and pH 10.0 on agar plates …

Functional metagenomic technologies for the discovery of novel enzymes for biomass degradation and biofuel production

H Wang, DJ Hart, Y An - BioEnergy Research, 2019 - Springer
As a long-term solution to fossil fuel depletion, deployment of renewable biofuel from plant
biomass degradation would provide significant economic benefits and energy security …

Highly efficient computationally derived novel metagenome α-amylase with robust stability under extreme denaturing conditions

S Ariaeenejad, B Zolfaghari… - Frontiers in …, 2021 - frontiersin.org
α-Amylases are among the very critical enzymes used for different industrial purposes. Most
α-amylases cannot accomplish the requirement of industrial conditions and easily lose their …