Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)

JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …

Medication‐related osteonecrosis of the jaw: a literature review and update

S Kuroshima, FA Al‐Omari, M Sasaki, T Sawase - Genesis, 2022 - Wiley Online Library
Since the initial description of medication‐related osteonecrosis of the jaw (MRONJ) almost
two decades ago, the potential pathophysiology and risk factors have been elaborated on in …

Establishment and assessment of rodent models of medication-related osteonecrosis of the jaw (MRONJ)

R Yan, R Jiang, L Hu, Y Deng, J Wen… - International journal of …, 2022 - nature.com
Medication-related osteonecrosis of the jaw (MRONJ) is primarily associated with
administering antiresorptive or antiangiogenic drugs. Despite significant research on …

Vascular endothelial growth factor: A translational view in oral non-communicable diseases

S Niklander, MJ Bordagaray, A Fernández… - Biomolecules, 2021 - mdpi.com
Vascular endothelial growth factors (VEGFs) are vital regulators of angiogenesis that are
expressed in response to soluble mediators, such as cytokines and growth factors. Their …

Preventing or controlling periodontitis reduces the occurrence of osteonecrosis of the jaw (ONJ) in rice rats (Oryzomys palustris)

EJ Castillo, JG Messer, AM Abraham, JM Jiron… - Bone, 2021 - Elsevier
Introduction Osteonecrosis of the jaw (ONJ) is an adverse event that requires association of
both systemic risk factors, such as powerful anti-resorptives (pARs; eg zoledronic acid …

Enamel Matrix Derivatives as an Adjunct to Alveolar Ridge Preservation—A Systematic Review

O Fakheran, KR Fischer, PR Schmidlin - Dentistry Journal, 2023 - mdpi.com
Purpose: To systematically assess the current evidence regarding the adjunctive application
of enamel matrix derivatives (EMDs) during alveolar ridge preservation (ARP) following …

Intermittent parathyroid hormone enhances the healing of medication-related osteonecrosis of the jaw lesions in rice rats

EJ Castillo, JM Jiron, CS Croft, DG Freehill… - Frontiers in …, 2023 - frontiersin.org
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
in patients treated with antiresorptives. Management of MRONJ is challenging, and no non …

Bone structural, biomechanical, and histomorphometric characteristics of the hindlimb skeleton in the marsh rice rat (Oryzomys palustris)

EJ Castillo, SM Croft, JM Jiron… - The Anatomical …, 2022 - Wiley Online Library
The rice rat (Oryzomys palustris) is a nonconventional laboratory rodent species used to
model some human bone disorders. However, no studies have been conducted to …

[PDF][PDF] 复合骨增量材料在牙槽嵴保存术中应用的研究进展

刘佳兴, 李武伟 - 大连医科大学学报, 2024 - journal.dmu.edu.cn
牙槽嵴保存术(ARP) 可以有效减少牙齿拔除后牙槽嵴的形态变化, 从而创造出有利于种植义齿
修复的软硬组织条件. 目前, 用于填充拔牙窝的复合骨增量材料主要为不同类型骨增量材料间的 …

Alteraciones óseas asociadas al Síndrome Metabólico en ratas: evaluación preclínica de un tratamiento oral con metformina

NE Wanionok - 2023 - sedici.unlp.edu.ar
Introducción. El síndrome metabólico (SM) se define por la presencia de tres o más factores
de riesgo cardiovascular en un individuo, incluyendo: obesidad central, triglicéridos …