This article reviews the current understanding of the mechanisms of calcineurin inhibitor–
induced hypertension. Already early after the introduction of cyclosporine in the 1980s …

Chronic kidney disease patient's progression to end-stage renal disease as well as their
high mortality are linked to cardiovascular disease. However, the high incidence rate of …

Hypertension is one of the most common cardiovascular co-morbidities after successful
kidney transplantation. It commonly occurs in patients with other metabolic diseases, such …

Background. Cardiovascular disease is a frequent complication after kidney transplantation
and represents the leading cause of mortality in this population. Material and Methods. We …

The widespread use of immunosuppressive drugs makes it possible to reduce inflammation
in autoimmune diseases, as well as prevent transplant rejection in organ recipients. Despite …

Background Chlorthalidone is a very effective antihypertensive drug, but it has not been
studied prospectively in kidney transplant recipients with hypertension. Recent data indicate …

Interstitial fibrosis with tubule atrophy (IF/TA) is the response to virtually any sustained
kidney injury and correlates inversely with kidney function and allograft survival. IF/TA is …

Aims: Calcineurin inhibitors (CNIs) are often used for solid organ transplantation recipients
or patients with immune‐mediated diseases. This systematic review and meta‐analysis aims …

Post-transplant hypertension (PTH) is a common complication in cyclosporine
immunosuppressed patients; however choosing the right antihypertensive medication is …

Background Angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor
blockers (ARBs) are widely prescribed after kidney transplantation, but evidence for an …