Traumatic brain injury (TBI) is a heterogeneous disorder that involves brain damage due to
external forces. TBI is the main factor of death and morbidity in young males with a high …

Virtually all cells in the organism secrete extracellular vesicles (EVs), a heterogeneous
population of lipid bilayer membrane-enclosed vesicles that transport and deliver payloads …

Background Spinal cord injury (SCI) can lead to severe motor and sensory dysfunction with
high disability and mortality. In recent years, mesenchymal stem cell (MSC)-secreted nano …

During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …

Stem cell-derived exosomes have recently been regarded as potential drugs for treating
spinal cord injury (SCI) by reducing reactive oxygen species (ROS) and suppressing M1 …

Neuroinflammation has been identified as a causative factor of multiple neurological
diseases. The nucleotide-binding oligomerization domain-, leucine-rich repeat-and pyrin …

Increasing data indicate that inflammation and alterations in glutamate neurotransmission
are two novel pathways to pathophysiology in mood disorders. The primary goal of this …

Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

Inflammasome is a complex of multiple proteins found in cytoplasm of the cells activated by
infectious and/or non-infectious stimuli. This complex involves caspase-1 activation, leading …

Background Spinal cord injury (SCI) is a catastrophic injury that can cause irreversible motor
dysfunction with high disability. Exosomes participate in the transport of miRNAs and play an …