The concept of 'lifestyle 'includes different factors such as nutrition, behavior, stress, physical activity, working habits, smoking and alcohol consumption. Increasing evidence shows that …
G Davey Smith, S Ebrahim - International journal of …, 2003 - academic.oup.com
Associations between modifiable exposures and disease seen in observational epidemiology are sometimes confounded and thus misleading, despite our best efforts to …
CpG methylation in vertebrates correlates with alterations in chromatin structure and gene silencing 1, 2, 3, 4. Differences in DNA-methylation status are associated with imprinting …
Azacytidine was first synthesized almost 40 years ago. It was demonstrated to have a wide range of anti-metabolic activities when tested against cultured cancer cells and to be an …
Methionine is an essential amino acid with many key roles in mammalian metabolism such as protein synthesis, methylation of DNA and polyamine synthesis. Restriction of methionine …
Folate is a water-soluble B-vitamin and enzymatic cofactor that is necessary for the synthesis of purine and thymidine nucleotides and for the synthesis of methionine from homocysteine …
M Belli, MA Tabocchini - International journal of molecular sciences, 2020 - mdpi.com
The present system of radiation protection assumes that exposure at low doses and/or low dose-rates leads to health risks linearly related to the dose. They are evaluated by a …
M Fenech - … Research/Fundamental and Molecular Mechanisms of …, 2012 - Elsevier
Folate plays a critical role in the prevention of uracil incorporation into DNA and hypomethylation of DNA. This activity is compromised when vitamin B12 concentration is …
YI Kim - The Journal of nutritional biochemistry, 1999 - Elsevier
Folate, a water-soluble B vitamin, has recently garnered much attention because of its purported role in the pathogenesis of cardiovascular disease, 1–4 neural tube defects, 5–7 …