The ease of performing both forward and reverse genetics in Saccharomyces cerevisiae,
along with its stable haploid state and short generation times, has made this budding yeast …

I present novel solutions to two different classes of computational problems that arise in the
study of complex cellular processes. The first problem arises in the context of planning large …

The genetic cross is a fundamental, flexible, and widely-used experimental technique to
create new mutant strains from existing ones. Surprisingly, the problem of how to efficiently …