Physical exercise associated with NO production: signaling pathways and significance in health and disease

EY Dyakova, LV Kapilevich, VG Shylko… - Frontiers in cell and …, 2015 - frontiersin.org
Here we review available data on nitric oxide (NO)-mediated signaling in skeletal muscle
during physical exercise. Nitric oxide modulates skeletal myocyte function, hormone …

Protective roles of bioactive peptides during ischemia-reperfusion injury: from bench to bedside

D Wu, J Wang, H Wang, A Ji, Y Li - Life sciences, 2017 - Elsevier
Abstract Ischemia-reperfusion (I/R) is a well-known pathological condition which may lead to
disability and mortality. I/R injury remains an unresolved and complicated situation in a …

Mitochondrial modulation of amplified preconditioning influences of remote ischemia plus erythropoietin against skeletal muscle ischemia/reperfusion injury in rats

AA Khalifa, MA Ali, NH Elsokkary, SS Elblehi… - Life Sciences, 2023 - Elsevier
Aims Skeletal muscle ischemia and reperfusion (SI/R) injury is relieved by interventions like
remote ischemic preconditioning (RIPC). Here, we tested the hypothesis that simultaneous …

Schisandrin B Prevents Hind Limb from Ischemia‐Reperfusion‐Induced Oxidative Stress and Inflammation via MAPK/NF‐κB Pathways in Rats

N Zhu, C Cai, A Zhou, X Zhao, Y Xiang… - BioMed research …, 2017 - Wiley Online Library
Schisandrin B (ScB), isolated from Schisandra chinensis (S. chinensis), is a traditional
Chinese medicine with proven cardioprotective and neuroprotective effects. However, it is …

[HTML][HTML] Protective effects of sonic hedgehog against ischemia/reperfusion injury in mouse skeletal muscle via AKT/mTOR/p70S6K signaling

Q Zeng, Q Fu, X Wang, Y Zhao, H Liu, Z Li… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Skeletal muscle ischemia/reperfusion (I/R) injury is a common and severe
disease. Sonic hedgehog (Shh) plays a critical role in post-natal skeletal muscle …

Regular aerobic exercise increased VEGF levels in both soleus and gastrocnemius muscles correlated with hippocampal learning and VEGF levels

A Karakilic, O Yüksel, S Kızıldağ… - Acta neurobiologiae …, 2021 - avesis.deu.edu.tr
Physical exercise improves learning and memory abilities by increasing the levels of several
growth factors in the hippocampus. One growth factor, vascular endothelial growth factor …

[HTML][HTML] Salvianolic acid a attenuates limb ischemia/reperfusion injury in skeletal muscle of rats

Y Xiang, S Ye, C Cai, J Chen, X Zhao, N Zhu… - Biomedicine & …, 2018 - Elsevier
Ischemia and reperfusion (I/R) injury can cause complications in applying blood flow
treatment for atherosclerosis occlusion syndrome. Platelet activation and inflammatory …

[PDF][PDF] Changes in the glutathione system's activity of internal organs in the first hours of experimental limb ischemia-reperfusion syndrome, combined with blood loss …

NV Volotovska, TC Nhokwara… - Здобутки клінічної i …, 2019 - irbis-nbuv.gov.ua
Blood loss of various genesis irreversibly leads to hypoxia, which in turn triggers the
activation of lipid peroxidation and, as a result, cell membranes are damaged. The use of a …

急性ST 段抬高型心肌梗死患者急诊经皮冠状动脉介入治疗前后血清血管内皮生长因子及高敏C 反应蛋白水平变化与术后再狭窄

王福华, 郭靖涛, 周江, 代燕燕 - 临床荟萃, 2014 - huicui.hebmu.edu.cn
目的: 联合检测急诊经皮冠状动脉介入治疗(PCI) 前后血清血管内皮生长因子(VEGF) 及高敏C
反应蛋白(hs-CRP) 水平变化, 旨在探讨急诊PCI 术前后血清VEGF 及hs-CRP …

Bioactive signaling in next-generation pharmacotherapies for heart failure: a review

KE Oatmen, MR Zile, JC Burnett, FG Spinale - JAMA cardiology, 2018 - jamanetwork.com
Importance The standard pharmacotherapy for heart failure (HF), particularly HF with
reduced ejection fraction (HFrEF), is primarily through the use of receptor antagonists …