Natural ageing of organisms and corresponding age-related diseases result mainly from
stem cell ageing and “inflammaging”. Mesenchymal stem cells (MSCs) exhibit very high …

The contribution of organelles to neural development has received increasing attention.
Studies have shown that organelles such as mitochondria, endoplasmic reticulum (ER) …

Cartilage defect is one of the most common pathogenesis of osteoarthritis (OA), a
degenerative joint disease that affects millions of people globally. Due to lack of nutrition …

In the early embryonic stages, Lin‐28 homologue A (Lin28a) is highly expressed and
declines as the embryo matures. As an RNA‐binding protein, Lin28a maintains some adult …

Introduction The analysis of the role of the mitochondria in oxidative damage and skin aging
has been a significant aspect of dermatological research. Mitochondria generate most …

Pluripotent stem cells of the mammalian epiblast and their cultured counterparts—embryonic
stem cells (ESCs) and epiblast stem cells (EpiSCs)—have the capacity to differentiate in all …

Introduction: The skin is the largest organ of the human body and fulfills protective, immune,
and metabolic functions. Skin function and barrier integrity are actively regulated through …

Urine-derived stem cells (USCs) are a promising source for regenerative medicine because
of their advantages such as easy and non-invasive collection from the human body, stable …

Chemotherapy is widely used clinically, however, its efficacy is often compromised by the
development of drug resistance, which arises from prolonged administration of drugs or …

Energy metabolism is crucial in stem cells as they harbor various metabolic pathways
depending on their developmental stages. Moreover, understanding the control of their self …