Non-vitamin K oral anticoagulants (NOACs) have revolutionized anticoagulant therapy,
offering improved safety and efficacy over traditional agents like warfarin. This review …

Cancer is associated with a high risk of venous thromboembolism (VTE) and its recurrence.
There is evidence that the prothrombotic fibrin clot phenotype, involving the formation of …

Background Cancer-associated thrombosis is a frequent complication in patients with
malignancies. While factor XI (FXI)/FXIa inhibition is efficacious in preventing postoperative …

Blood coagulation and innate immunity are closely interrelated. At sites of inflammation,
DNA and myeloperoxidase (MPO) are released from polymorphonuclear leukocytes (PMNs) …

Dabigatran (DAB) is an orally administered thrombin inhibitor. Both DAB and its main
metabolite dabigatran acylglucuronide (DABG) have established anticoagulant effects …