Objective Sensitization of mismatch repair (MMR)-deficient colorectal cancer (CRC) cells by
5-Fluorouracil (5-FU) is well-documented. But not much is known about the treatment of …

Despite recent advancements in the diagnosis and treatment of breast cancer (BC), patient
outcomes in terms of survival, recurrence, and disease progression remain suboptimal. A …

Tumor associated macrophages (TAMs) and cancer-associated fibroblasts (CAFs) in the
tumor microenvironment secrete several cytokines, which involved in tumor initiation …

Introduction Gastric cancer (GC) is one of the leading causes of cancer-related death
worldwide. Recently, targeted therapies including PD1 (programmed cell death 1) …

Cancer cells merely exist in isolation; rather, they exist in an intricate microenvironment
composed of blood vessels, signalling molecules, immune cells, stroma, fibroblasts, and the …

Heat shock proteins (HSP) are a large family of peptide proteins that are widely found in
cells. Studies have shown that the expression and function of HSPs in cells are very …

Aim: This study aimed to determine if quinacrine–gold hybrid nanoparticles (QAuNPs)+ near-
infrared (NIR) deregulate HSP-70/P300 complex-mediated H3K14 acetylation in estrogen …

Background The occurrence of epithelial-mesenchymal transition (EMT) and immune
evasion is considered to contribute to poor prognosis in lung adenocarcinoma (LUAD) …

DNA polymerase β (Polβ) is crucial for the base excision repair (BER) pathway of DNA
damage repair and is an attractive target for suppressing tumorigenesis as well as …

Surgery, chemotherapy, radiotherapy, targeted therapy and immunotherapy are all
examples of standard cancer treatments. However, achieving successful cancer treatment is …