Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#
Abstract Purpose This Position Paper aims to review and discuss the available data on
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …
Glycopeptide antibiotics: back to the future
Glycopeptide antibiotics have been a key weapon in the fight against bacterial infections for
over half a century, with the progenitors, vancomycin (1) and teicoplanin (2), still used …
over half a century, with the progenitors, vancomycin (1) and teicoplanin (2), still used …
Therapeutic drug monitoring of anti-infective agents in critically ill patients
NGL Jager, RM van Hest, J Lipman… - Expert review of …, 2016 - Taylor & Francis
Initial adequate anti-infective therapy is associated with significantly improved clinical
outcomes for patients with severe infections. However, in critically ill patients, several …
outcomes for patients with severe infections. However, in critically ill patients, several …
Pharmacokinetics and target attainment of antibiotics in critically ill children: a systematic review of current literature
SJF Hartman, RJ Brüggemann, L Orriëns, N Dia… - Clinical …, 2020 - Springer
Background Pharmacokinetics (PK) are severely altered in critically ill patients due to
changes in volume of distribution (Vd) and/or drug clearance (Cl). This affects the target …
changes in volume of distribution (Vd) and/or drug clearance (Cl). This affects the target …
Clinical practice guidelines for therapeutic drug monitoring of teicoplanin: a consensus review by the Japanese Society of Chemotherapy and the Japanese Society of …
Y Hanai, Y Takahashi, T Niwa, T Mayumi… - Journal of …, 2022 - academic.oup.com
Background Owing to its low risk of adverse effects, teicoplanin has been extensively used
in patients with infections caused by MRSA. To promote the better management of patients …
in patients with infections caused by MRSA. To promote the better management of patients …
Non-oncotic properties of albumin. A multidisciplinary vision about the implications for critically ill patients
Introduction: Effective resuscitation with human albumin solutions is achieved with less fluid
than with crystalloid solutions. However, the role of albumin in today's critical care unit is …
than with crystalloid solutions. However, the role of albumin in today's critical care unit is …
Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill
D Tsai, J Lipman, JA Roberts - Current opinion in critical care, 2015 - journals.lww.com
Optimization of antimicrobial dosing in accordance with pharmacokinetics/
pharmacodynamics targets can improve survival and clinical cure. Dosing regimens for …
pharmacodynamics targets can improve survival and clinical cure. Dosing regimens for …
Hypoalbuminemia and pharmacokinetics: when the misunderstanding of a fundamental concept leads to repeated errors over decades
P Gandia, S Decheiver, M Picard, R Guilhaumou… - Antibiotics, 2023 - mdpi.com
Surprisingly, misinterpretation of the influence of hypoalbuminemia on pharmacokinetics
and the clinical effects of drugs seems to be a current problem, even though …
and the clinical effects of drugs seems to be a current problem, even though …
Understanding pk/pd
JA Roberts, FS Taccone, J Lipman - Intensive care medicine, 2016 - Springer
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in Menu Find a journal Publish with us Search Cart 1.Home 2.Intensive Care Medicine 3.Article …
in Menu Find a journal Publish with us Search Cart 1.Home 2.Intensive Care Medicine 3.Article …
Old and new glycopeptide antibiotics: From product to gene and back in the post-genomic era
GL Marcone, E Binda, F Berini, F Marinelli - Biotechnology advances, 2018 - Elsevier
Glycopeptide antibiotics are drugs of last resort for treating severe infections caused by multi-
drug resistant Gram-positive pathogens. First-generation glycopeptides (vancomycin and …
drug resistant Gram-positive pathogens. First-generation glycopeptides (vancomycin and …