MicroRNA-mediated epigenetic regulation of rheumatoid arthritis susceptibility and pathogenesis

C Chang, L Xu, R Zhang, Y Jin, P Jiang, K Wei… - Frontiers in …, 2022 - frontiersin.org
MicroRNAs (miRNAs) play crucial roles in regulating the transcriptome and development of
rheumatoid arthritis (RA). Currently, a comprehensive map illustrating how miRNAs regulate …

The role of microRNAs in the pathogenesis of autoimmune diseases

JQ Chen, G Papp, P Szodoray, M Zeher - Autoimmunity reviews, 2016 - Elsevier
MicroRNAs (miRNAs) are single-stranded, endogenous non-coding small RNAs, ranging
from 18 to 25 nucleotides in length. Growing evidence suggests that miRNAs are essential …

MicroRNAs in rheumatoid arthritis: altered expression and diagnostic potential

AV Churov, EK Oleinik, M Knip - Autoimmunity reviews, 2015 - Elsevier
Rheumatoid arthritis (RA) is a polygenic disease characterized by autoimmunity and
systemic inflammation with progressive impairment of joints that results in lifelong disability …

Epigenetic changes in the pathogenesis of rheumatoid arthritis

MV Nemtsova, DV Zaletaev, IV Bure… - Frontiers in …, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

[HTML][HTML] DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging

F Olivieri, MC Albertini, M Orciani, A Ceka, M Cricca… - Oncotarget, 2015 - ncbi.nlm.nih.gov
A major issue in aging research is how cellular phenomena affect aging at the systemic
level. Emerging evidence suggests that DNA damage response (DDR) signaling is a key …

[HTML][HTML] microRNA diagnostic panel for Alzheimer's disease and epigenetic trade-off between neurodegeneration and cancer

S Nagaraj, KM Zoltowska, K Laskowska-Kaszub… - Ageing research …, 2019 - Elsevier
Abstract microRNAs (miRNAs) have been extensively studied as potential biomarkers for
Alzheimer's disease (AD). Their profiles have been analyzed in blood, cerebrospinal fluid …

miR-221-3p drives the shift of M2-macrophages to a pro-inflammatory function by suppressing JAK3/STAT3 activation

L Quero, AN Tiaden, E Hanser, J Roux, A Laski… - Frontiers in …, 2020 - frontiersin.org
Objectives: Macrophages are conventionally classified as pro-inflammatory (M1) and anti-
inflammatory (M2) functional types. There is evidence for a predominance of macrophages …

Implications the Role of miR-155 in the Pathogenesis of Autoimmune Diseases

S Pashangzadeh, M Motallebnezhad… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are small noncoding conserved RNAs containing 19 to 24 nucleotides
that are regulators of post-translational modifications and are involved in the majority of …

Rheumatoid arthritis and miRNAs: a critical review through a functional view

MC Moran-Moguel, S Petarra-del Rio… - Journal of …, 2018 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic autoimmune disease with severe joint inflammation
and destruction associated with an inflammatory environment. The etiology behind RA …

Role of miR-155 in inflammatory autoimmune diseases: a comprehensive review

WD Xu, SY Feng, AF Huang - Inflammation Research, 2022 - Springer
Purpose MiR-155 is a member of the microRNAs (miRNAs) family and regulates gene
expression post-transcriptionally by binding to the 3'UTR of target mRNA. MiR-155 has a …