Targeting vascular calcification in chronic kidney disease

AJ Nelson, P Raggi, M Wolf, AM Gold… - Basic to Translational …, 2020 - jacc.org
Cardiovascular (CV) disease remains an important cause of morbidity and mortality for
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …

Vegetable-based diets for chronic kidney disease? It is time to reconsider

A Cases, S Cigarrán-Guldrís, S Mas, E Gonzalez-Parra - Nutrients, 2019 - mdpi.com
Traditional dietary recommendations to renal patients limited the intake of fruits and
vegetables because of their high potassium content. However, this paradigm is rapidly …

Pathological mechanisms of kidney disease in ageing

T Yamamoto, Y Isaka - Nature Reviews Nephrology, 2024 - nature.com
The kidney is a metabolically active organ that requires energy to drive processes such as
tubular reabsorption and secretion, and shows a decline in function with advancing age …

A randomized trial of magnesium oxide and oral carbon adsorbent for coronary artery calcification in predialysis CKD

Y Sakaguchi, T Hamano, Y Obi, C Monden… - Journal of the …, 2019 - journals.lww.com
Background Developing strategies for managing coronary artery calcification (CAC) in
patients with CKD is an important clinical challenge. Experimental studies have …

The effect of increasing dialysate magnesium on serum calcification propensity in subjects with end stage kidney disease: a randomized, controlled clinical trial

I Bressendorff, D Hansen, M Schou… - Clinical Journal of the …, 2018 - journals.lww.com
Results Fifty-nine subjects were enrolled in the trial, and of these, 57 completed the
intervention and were analyzed for the primary outcome. In the standard dialysate …

Calciprotein particles: balancing mineral homeostasis and vascular pathology

AG Kutikhin, L Feenstra, AE Kostyunin… - … , and vascular biology, 2021 - Am Heart Assoc
Hypercalcemia and hyperphosphatemia associate with an elevated risk of cardiovascular
events, yet the pathophysiological basis of this association is unclear. Disturbed mineral …

Magnesium administration in chronic kidney disease

EA Vermeulen, MG Vervloet - Nutrients, 2023 - mdpi.com
Awareness of the clinical relevance of magnesium in medicine has increased over the last
years, especially for people with chronic kidney disease (CKD), due to magnesium's role in …

Plant-dominant low protein diet: A potential alternative dietary practice for patients with chronic kidney disease

Y Sakaguchi, JY Kaimori, Y Isaka - Nutrients, 2023 - mdpi.com
Dietary protein restriction has long been a cornerstone of nutritional therapy for patients with
chronic kidney diseases (CKD). However, the recommended amount of dietary protein …

Inverse J-shaped relationship of dietary carbohydrate intake with serum klotho in Nhanes 2007–2016

L Xiang, M Wu, Y Wang, S Liu, Q Lin, G Luo, L Xiao - Nutrients, 2023 - mdpi.com
Background: The relationship between dietary carbohydrate intake and serum Klotho levels,
an aging biomarker, remains uncertain. Objective: This study aimed to investigate the …

[HTML][HTML] Magnesium prevents vascular calcification in Klotho deficiency

AD Ter Braake, AE Smit, C Bos, AE van Herwaarden… - Kidney International, 2020 - Elsevier
Klotho knock-out mice are an important model for vascular calcification, which is associated
with chronic kidney disease. In chronic kidney disease, serum magnesium inversely …