Exercise is medicine for nonalcoholic fatty liver disease: exploration of putative mechanisms

JW Heinle, K DiJoseph, A Sabag, S Oh, SR Kimball… - Nutrients, 2023 - mdpi.com
Exercise remains a key component of nonalcoholic fatty liver disease (NAFLD) treatment.
The mechanisms that underpin improvements in NAFLD remain the focus of much …

Targeting the Adipose Tissue–Liver–Gut Microbiota Crosstalk to Cure MASLD

D Gabbia, S De Martin - Biology, 2023 - mdpi.com
Simple Summary Dysfunctional gut microbiota leads to the activation of multiple pathways in
the gut and in the liver that sustain hepatic inflammation and are involved in the …

Serum fibroblast growth factor 21 is markedly decreased following exercise training in patients with biopsy-proven nonalcoholic steatohepatitis

JG Stine, JE Welles, S Keating, Z Hussaini, C Soriano… - Nutrients, 2023 - mdpi.com
Background and Aims: Exercise remains a key component of nonalcoholic fatty liver disease
(NAFLD) treatment. However, mechanisms underpinning the improvements in NAFLD seen …

Ameliorative role of bioactive phytoconstituents targeting obesity associated NAFLD by modulation of inflammation and lipogenesis pathways: a comprehensive …

PA Barbhuiya, S Sen, MP Pathak - Phytochemistry Reviews, 2023 - Springer
By 2025, the projected global obesity rates for both men and women are 18% and 21%,
respectively. Obesity raises the risk of several comorbidities like cardiovascular disease …

Biomarkers of hepatic dysfunction and cardiovascular risk

TB Lee Jr, MTW Kueh, V Jain, AC Razavi… - Current Cardiology …, 2023 - Springer
Abstract Purpose of Review The objective of this manuscript is to examine the current
literature on non-alcoholic fatty liver disease (NAFLD) biomarkers and their correlation with …

Review of current and new drugs for the treatment of metabolic-associated fatty liver disease

R Gish, JG Fan, Z Dossaji, J Fichez, T Laeeq… - Hepatology …, 2024 - Springer
In the past 3 decades, metabolic-associated fatty liver disease (MAFLD) has emerged as a
widespread liver condition, with its global prevalence on the rise. It ranks as a leading …

Relevant Aspects of Combined Protocols for Prevention of N (M) AFLD and Other Non‐Communicable Diseases

LA Videla, R Valenzuela… - Molecular Nutrition & …, 2024 - Wiley Online Library
Obesity is a global health issue characterized by the excessive fat accumulation, leading to
an increased risk of chronic noncommunicable diseases (NCDs), including metabolic …

Investigation of FGF21 mRNA levels and relative mitochondrial DNA copy number levels and their relation in nonalcoholic fatty liver disease: a case-control study

M Houshmand, V Zeinali, A Hosseini, A Seifi… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Although the exact mechanisms of nonalcoholic fatty liver disease (NAFLD) are
not fully understood, numerous pieces of evidence show that the variations in mitochondrial …

[HTML][HTML] Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice …

ER McGlone, DCD Hope, I Davies, M Dore… - Biomedicine & …, 2024 - Elsevier
Objectives Co-agonists at the glucagon-like peptide-1 and glucagon receptors
(GLP1R/GCGR) show promise as treatments for metabolic dysfunction-associated steatotic …

[HTML][HTML] FGF21: A Sharp Weapon in the Process of Exercise to Improve NAFLD

Z Wang, T Sun, J Yu, S Li, L Gong… - Frontiers in Bioscience …, 2023 - imrpress.com
Nonalcoholic fatty liver disease (NAFLD) is a pathological syndrome characterized by
excessive fat deposition in hepatocytes. A sedentary lifestyle is a major risk factor for …