[HTML][HTML] Tau interactome and RNA binding proteins in neurodegenerative diseases

T Kavanagh, A Halder, E Drummond - Molecular neurodegeneration, 2022 - Springer
Pathological tau aggregation is a primary neuropathological feature of many
neurodegenerative diseases. Intriguingly, despite the common presence of tau aggregates …

[PDF][PDF] Alzheimer's Disease Puzzle: Delving into Pathogenesis Hypotheses.

M Nasb, W Tao, N Chen - Aging and Disease, 2024 - researchgate.net
Alzheimer's disease (AD) is a prevalent neurodegenerative disease characterized by both
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …

Liquid‐Liquid Phase Separation Promotes Protein Aggregation and Its Implications in Ferroptosis in Parkinson's Disease Dementia

M Li, Y Fan, Q Li, X Wang, L Zhao… - Oxidative Medicine and …, 2022 - Wiley Online Library
The pathological features of PDD are represented by dopaminergic neuronal death and
intracellular α‐synuclein (α‐syn) aggregation. The interaction of iron accumulation with α …

microRNA and circRNA in Parkinson's disease and atypical parkinsonian syndromes

A Bougea, L Stefanis - Advances in Clinical Chemistry, 2023 - Elsevier
Abstract Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP) are
atypical parkinsonian syndromes (APS) with various clinical phenotypes and considerable …

[HTML][HTML] Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer's Disease and Related …

J Hill, KE Shalaby, SW Bihaqi, BH Alansi… - International Journal of …, 2023 - mdpi.com
The field of Alzheimer's disease (AD) has witnessed recent breakthroughs in the
development of disease-modifying biologics and diagnostic markers. While …

[HTML][HTML] Interpretable Classification of Tauopathies with a Convolutional Neural Network Pipeline Using Transfer Learning and Validation against Post-Mortem Clinical …

L Diaz-Gomez, AE Gutierrez-Rodriguez… - Current Issues in …, 2022 - mdpi.com
Neurodegenerative diseases, tauopathies, constitute a serious global health problem. The
etiology of these diseases is unclear and an increase in their incidence has been projected …

[HTML][HTML] Concomitant neuronal tau deposition and FKBP52 decrease is an early feature of different human and experimental tauopathies

G Meduri, K Guillemeau, C Daguinot… - Journal of …, 2023 - content.iospress.com
Background: Pathological tau proteins constitute neurofibrillary tangles that accumulate in
tauopathies including Alzheimer's disease (AD), progressive supranuclear palsy (PSP), and …

[HTML][HTML] Connecting cellular mechanisms and extracellular vesicle cargo in traumatic brain injury

N Ollen-Bittle, AD Roseborough, W Wang… - Neural Regeneration …, 2024 - journals.lww.com
Traumatic brain injury is followed by a cascade of dynamic and complex events occurring at
the cellular level. These events include: diffuse axonal injury, neuronal cell death, blood …

[HTML][HTML] A Novel Automatic Quantification Protocol for Biomarkers of Tauopathies in the Hippocampus and Entorhinal Cortex of Post-Mortem Samples Using an …

LA Campero-Garcia, JA Cantoral-Ceballos… - Biology, 2022 - mdpi.com
Simple Summary Tauopathies is a term coined to describe an umbrella of disorders
characterized by abnormal Tau polypeptide deposits in neurons, glial cells, and extracellular …

连接创伤性脑损伤中的细胞机制和细胞外囊泡货物

N Ollen-Bittle, AD Roseborough, W Wang… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
Traumatic brain injury is followed by a cascade of dynamic and complex events occurring at
the cellular level. These events include: diffuse axonal injury, neuronal cell death, blood …