[HTML][HTML] Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome
Antibiotic resistance is a major health concern globally and has been estimated to cause 10
million deaths worldwide by year 2050 if the current trend of inappropriate and excessive …
million deaths worldwide by year 2050 if the current trend of inappropriate and excessive …
Signals, regulatory networks, and materials that build and break bacterial biofilms
E Karatan, P Watnick - Microbiology and molecular biology …, 2009 - Am Soc Microbiol
Biofilms are communities of microorganisms that live attached to surfaces. Biofilm formation
has received much attention in the last decade, as it has become clear that virtually all types …
has received much attention in the last decade, as it has become clear that virtually all types …
Adaptive mutability of colorectal cancers in response to targeted therapies
The emergence of drug resistance limits the efficacy of targeted therapies in human tumors.
The prevalent view is that resistance is a fait accompli: when treatment is initiated, cancers …
The prevalent view is that resistance is a fait accompli: when treatment is initiated, cancers …
Post-stress bacterial cell death mediated by reactive oxygen species
Y Hong, J Zeng, X Wang, K Drlica… - Proceedings of the …, 2019 - National Acad Sciences
Antimicrobial efficacy, which is central to many aspects of medicine, is being rapidly eroded
by bacterial resistance. Since new resistance can be induced by antimicrobial action, highly …
by bacterial resistance. Since new resistance can be induced by antimicrobial action, highly …
Cell Death in Pseudomonas aeruginosa Biofilm Development
JS Webb, LS Thompson, S James… - Journal of …, 2003 - Am Soc Microbiol
Bacteria growing in biofilms often develop multicellular, three-dimensional structures known
as microcolonies. Complex differentiation within biofilms of Pseudomonas aeruginosa …
as microcolonies. Complex differentiation within biofilms of Pseudomonas aeruginosa …
Mutation as a stress response and the regulation of evolvability
RS Galhardo, PJ Hastings… - Critical reviews in …, 2007 - Taylor & Francis
Our concept of a stable genome is evolving to one in which genomes are plastic and
responsive to environmental changes. Growing evidence shows that a variety of …
responsive to environmental changes. Growing evidence shows that a variety of …
Stress-induced mutagenesis in bacteria
PL Foster - Critical reviews in biochemistry and molecular biology, 2007 - Taylor & Francis
Bacteria spend their lives buffeted by changing environmental conditions. To adapt to and
survive these stresses, bacteria have global response systems that result in sweeping …
survive these stresses, bacteria have global response systems that result in sweeping …
Gamblers: an antibiotic-induced evolvable cell subpopulation differentiated by reactive-oxygen-induced general stress response
Antibiotics can induce mutations that cause antibiotic resistance. Yet, despite their
importance, mechanisms of antibiotic-promoted mutagenesis remain elusive. We report that …
importance, mechanisms of antibiotic-promoted mutagenesis remain elusive. We report that …
Stress-induced mutagenesis in bacteria
The evolutionary significance of stress-induced mutagenesis was evaluated by studying
mutagenesis in aging colonies (MAC) of Escherichia coli natural isolates. A large fraction of …
mutagenesis in aging colonies (MAC) of Escherichia coli natural isolates. A large fraction of …
Oxidative stress-induced DNA damage and DNA repair mechanisms in mangrove bacteria exposed to climatic and heavy metal stressors
Bacteria thriving in the mangrove ecosystem are major drivers of elemental cycles. Climate
change and environmental stressors (heavy metals) influence the performance of these …
change and environmental stressors (heavy metals) influence the performance of these …