Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …
[PDF][PDF] Thymoquinone and curcumin prevent gentamicin-induced liver injury by attenuating oxidative stress, inflammation and apoptosis
This study was conducted to assess the preventive effect of two plant constituents,
thymoquinone and curcumin, on gentamicin-induced deleterious effect on liver function …
thymoquinone and curcumin, on gentamicin-induced deleterious effect on liver function …
Silymarin, an antioxidant flavonoid, protects the liver from the toxicity of the anticancer drug paclitaxel
One of the biggest factors that negatively affect the cancer treatment plan is the toxic effects
of chemotherapeutics on non-target cells and tissues. This information prompted us to …
of chemotherapeutics on non-target cells and tissues. This information prompted us to …
Potential therapeutic effect of thymoquinone and/or bee pollen on fluvastatin-induced hepatitis in rats
Hepatitis is one of earlier, but serious, signs of liver damage. High doses of statins for a long
time can induce hepatitis. This study aimed to evaluate and compare the therapeutic …
time can induce hepatitis. This study aimed to evaluate and compare the therapeutic …
Thymoquinone ameliorates the immunological and histological changes induced by exposure to imidacloprid insecticide
Previous studies have shown that thymoquinone (TQ) exerts protective effects in some
models of pesticide-induced immunotoxicity. However, no data exist regarding its possible …
models of pesticide-induced immunotoxicity. However, no data exist regarding its possible …
Hepato-protective effects of thymoquinone and beta-aminoisobutyric acid in streptozocin induced diabetic rats
İ Aktaş, F Mehmet Gür - Biotechnic & Histochemistry, 2022 - Taylor & Francis
We investigated the hepato-protective effects of thymoquinone (TQ) and beta-
aminoisobutyric acid (BAIBA). We used five groups of 8-week-old male rats: untreated …
aminoisobutyric acid (BAIBA). We used five groups of 8-week-old male rats: untreated …
Misoprostol alleviates paclitaxel-induced liver damage through its antioxidant and anti-apoptotic effects
Backgrounds Anticancer drugs may damage non-target cells and tissues. One of the biggest
reasons for changing or stopping chemotherapy regimens is these adverse effects …
reasons for changing or stopping chemotherapy regimens is these adverse effects …
The ameliorative effects of thymoquinone and beta-aminoisobutyric acid on streptozotocin-induced diabetic cardiomyopathy
Diabetic cardiomyopathy (DCM) is a cardiac dysfunction observed in a patient with diabetes
that may lead to heart failure. No specific treatment has yet been tested in DCM. Therefore …
that may lead to heart failure. No specific treatment has yet been tested in DCM. Therefore …
Bromelain ameliorates D-galactosamine-induced acute liver injury: role of SIRT1/LKB1/AMPK, GSK3β/Nrf2 and NF-κB p65/TNF-α/caspase-8,-9 signalling pathways
MA Didamoony, AM Atwa… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives The present research focused on estimating, for the first time, the potential
protective effects of bromelain against D-galactosamine-induced acute liver injury in rats as …
protective effects of bromelain against D-galactosamine-induced acute liver injury in rats as …
Occurrence and bioactivity diversity of thymoquinone: an overview
Nigella sativa L. seeds are traditionally known for their ability to cure different diseases
including airway disorders, back pain and chronic headache, paralysis, diabetes …
including airway disorders, back pain and chronic headache, paralysis, diabetes …