The day-to-day practice of MMR and MSI assessment in colorectal adenocarcinoma: what we know and what we still need to explore

P Parente, F Grillo, A Vanoli, MC Macciomei… - Dig. Dis, 2023 - karger.com
Abstract Background. The DNA Mismatch repair (MMR) system is a highly preserved protein
complex recognizing short insertions, short deletions and single base mismatches during …

Microsatellite instable colorectal adenocarcinoma diagnostics: the advent of liquid biopsy approaches

C Ceccon, V Angerilli, C Rasola, L Procaccio… - Frontiers in …, 2022 - frontiersin.org
The introduction of immunotherapy has revolutionized the oncological targeted therapy
paradigm. Microsatellite instability (MSI) identifies a subgroup of colorectal cancers (CRCs) …

Clinical testing for mismatch repair in neoplasms using multiple laboratory methods

RK Yang, H Chen, S Roy-Chowdhuri, A Rashid… - Cancers, 2022 - mdpi.com
Simple Summary There are limited studies that incorporate genetic/epigenetic alterations
into the assessment of the microsatellite instability (MSI) and mismatch repair (MMR) …

Diagnostic performance of Idylla MSI test in colorectal cancer biopsies

I Ukkola, P Nummela, M Kero, A Ristimäki - Diagnostic Pathology, 2023 - Springer
Universal testing for microsatellite instability (MSI) is recommended in colorectal cancer
(CRC) to screen for Lynch syndrome and to guide optimal treatment and follow-up of the …

Molecular Profiling of H-MSI/dMMR/for Endometrial Cancer Patients:“New Challenges in Diagnostic Routine Practice”

R Adorisio, G Troncone, M Barberis, F Pepe - Journal of Molecular …, 2024 - mdpi.com
Endometrial cancer (EC) represents one of the most newly diagnosed cancers across
gynecological malignancies. In particular, a plethora of risk factors (both biological and …

[HTML][HTML] Impact of DNA mismatch repair proteins deficiency on number and ratio of lymph nodal metastases in colorectal adenocarcinoma

F Zannier, V Angerilli, G Spolverato, S Brignola… - … -Research and Practice, 2023 - Elsevier
Background Approximately 15% of colorectal adenocarcinomas (CRCs) are characterized
by an altered expression of DNA mismatch repair (MMR) proteins (ie MMR deficiency …

TCOF1 is Identified to be an Unfavorable Biomarker and is Associated with Molecular Classification in Endometrial Cancer

C Xu, Q Wang - 2022 - repository.unar.ac.id
TCOF1 is Identified to be an Unfavorable Biomarker and is Associated with Molecular
Classification in Endometrial Cancer Caiqiu Xu1,†, Qinghai Wang1,†, Yilin Zhang1, Qirun …