Mitochondrial spare respiratory capacity: mechanisms, regulation, and significance in non‐transformed and cancer cells

P Marchetti, Q Fovez, N Germain, R Khamari… - The FASEB …, 2020 - Wiley Online Library
Mitochondrial metabolism must constantly adapt to stress conditions in order to maintain
bioenergetic levels related to cellular functions. This absence of proper adaptation can be …

[HTML][HTML] Recent advances in mitochondrial diseases: From molecular insights to therapeutic perspectives

AM Aldossary, EA Tawfik, MN Alomary… - Saudi Pharmaceutical …, 2022 - Elsevier
Mitochondria are double-membraned cytoplasmic organelles that are responsible for the
production of energy in eukaryotic cells. The process is completed through oxidative …

Neonatal-onset mitochondrial disease: clinical features, molecular diagnosis and prognosis

T Ebihara, T Nagatomo, Y Sugiyama… - Archives of Disease in …, 2022 - fn.bmj.com
Objective Neonatal-onset mitochondrial disease has not been fully characterised owing to
its heterogeneity. We analysed neonatal-onset mitochondrial disease in Japan to clarify its …

An Increase in Vascular Stiffness Is Positively Associated With Mitochondrial Bioenergetics Impairment of Peripheral Blood Mononuclear Cells in the Older Adults

T Attachaipanich, S Sriwichaiin, N Apaijai… - The Journals of …, 2024 - academic.oup.com
The cardio-ankle vascular index (CAVI) is a noninvasive parameter reflecting vascular
stiffness. CAVI correlates with the burden of atherosclerosis and future cardiovascular …

Clinically relevant oxygraphic assay to assess mitochondrial energy metabolism in acute myeloid leukemia patients

Q Fovez, W Laine, L Goursaud, C Berthon, N Germain… - Cancers, 2021 - mdpi.com
Simple Summary AML mitochondrial oxidative phosphorylation has recently been identified
as a biological property that influences the response to antitumor therapy. In the present …

Establishment of a platform for measuring mitochondrial oxygen consumption rate for cardiac mitochondrial toxicity

CW Kim, HJ Lee, D Ahn, RE Go, KC Choi - Toxicological Research, 2022 - Springer
The heart has an abundance of mitochondria since cardiac muscles require copious
amounts of energy for providing continuous blood through the circulatory system, thereby …

Estudio estructural y funcional de la proteína Disrupted in Schizophrenia 1 (DISC1) en mode/os ce/u/ares y murinos. lmplicaciones en enfermedades del …

L Ruiz Guerra - 2022 - dspace.uib.es
[spa] Disrupted in Schizophrenia 1 (DISC1) es uno de los genes más comúnmente
asociados a la susceptibilidad de padecer un trastorno mental grave, como esquizofrenia …

Clinical presentation and genetic characterisation of mitochondrial disease in Kuwait

AA Alahmad - 2020 - theses.ncl.ac.uk
Mitochondrial disorders are a group of clinically heterogenous conditions affecting multiple
systems with a prevalence that is estimated to affect 1 in 4,300 individuals. Mitochondrial …

A useful method to diagnose Pearson syndrome mimicking Diamond–Blackfan anemia.

T Nishimura, A Yamada, M Utoyama… - Pediatrics …, 2021 - search.ebscohost.com
The article focuses on Pearson syndrome (PS) is a multisystem disorder characterized by
hematological abnormalities, exocrine pancreatic dysfunction, and lactic acidosis. Topics …