Druggable lipid GPCRs: past, present, and prospects
H Mizuno, Y Kihara - Druggable Lipid Signaling Pathways, 2020 - Springer
G protein-coupled receptors (GPCRs) have seven transmembrane spanning domains and
comprise the largest superfamily with~ 800 receptors in humans. GPCRs are attractive …
comprise the largest superfamily with~ 800 receptors in humans. GPCRs are attractive …
Functional movements of the GABA type A receptor
We have performed a parallel tempering crankshaft motion Monte Carlo simulation on a
model of the GABA type A receptor with the aim of exploring a wide variety of local …
model of the GABA type A receptor with the aim of exploring a wide variety of local …
Correlated conformational dynamics of the human GluN1-GluN2A type N-methyl-D-aspartate (NMDA) receptor
N-Methyl-D-aspartate receptors (NMDARs) are glutamate-gated ion channels found in the
nerve cell membranes. As a result of overexcitation of NMDARs, neuronal death occurs and …
nerve cell membranes. As a result of overexcitation of NMDARs, neuronal death occurs and …