[HTML][HTML] Natural bioactive products as promising therapeutics: A review of natural product-based drug development

CB Aware, DN Patil, SS Suryawanshi, PR Mali… - South African Journal of …, 2022 - Elsevier
Since ancient times, natural medicines have had paramount importance in bolstering
biotherapeutics to treat various diseases. The World Health Organization (WHO) revealed …

Hairy root culture technology: applications, constraints and prospect

S Gantait, E Mukherjee - Applied Microbiology and Biotechnology, 2021 - Springer
Hairy root (HR) culture, a successful biotechnology combining in vitro tissue culture with
recombinant DNA machinery, is intended for the genetic improvement of plants. This …

Enhanced production of bioactive plumbagin in hairy root cultures and adventitious root cultures of Plumbago zeylanica L. by a novel apocarotenoid elicitor, α-ionone

A Kumar, A Kumari, P Demiwal, P Roy… - Industrial Crops and …, 2023 - Elsevier
Plumbagin, a medicinally important secondary metabolite is produced in the roots of
Plumbago zeylanica Linn. Natural harvest of plumbagin from roots is a destructive process …

Plant tissue culture: applications in plant improvement and conservation

A Shahzad, S Parveen, S Sharma, A Shaheen… - Plant Biotechnology …, 2017 - Springer
Plant tissue culture is a significant contribution in micropropagation of ornamental and forest
trees, production of pharmaceutically interesting compounds and plant breeding for …

Methyl jasmonate elicits the solasodine production and anti-oxidant activity in hairy root cultures of Solanum trilobatum L.

J Shilpha, L Satish, M Kavikkuil, MJV Largia… - Industrial Crops and …, 2015 - Elsevier
Hairy root cultures of Solanum trilobatum L. were established from leaf explants infected with
Agrobacterium rhizogenes strains viz., MTCC 532, MTCC 2364 and ATCC A 4. Initially 27 …

Bioproduction process of natural products and biopharmaceuticals: Biotechnological aspects

I Süntar, S Çetinkaya, ÜS Haydaroğlu… - Biotechnology …, 2021 - Elsevier
Decades of research have been put in place for developing sustainable routes of
bioproduction of high commercial value natural products (NPs) on the global market. In the …

A critical review on biotechnological interventions for production and yield enhancement of secondary metabolites in hairy root cultures

M Halder, D Roychowdhury, S Jha - Hairy Roots: An Effective Tool of Plant …, 2018 - Springer
In the past three decades, differentiated hairy root culture-related researches gained a great
attention due to the equal or greater bio-production capacity of low amount, high-value …

Influence of different Agrobacterium rhizogenes strains on hairy root induction and analysis of phenolic and flavonoid compounds in marshmallow (Althaea officinalis …

P Tavassoli, A Safipour Afshar - 3 Biotech, 2018 - Springer
Hairy roots were induced in Althea officinalis using Agrobacterium rhizogenes, strains A4,
A13, ATCC15834, and ATCC15834 (GUS). The leaf, petiole and shoot explants of …

Using hairy roots for production of valuable plant secondary metabolites

L Tian - Filaments in bioprocesses, 2015 - Springer
<? xm-replace_text {Heading}?> Abstract Plants synthesize a wide variety of natural
products, which are traditionally termed secondary metabolites and, more recently, coined …

Chemical Profile of Cell Cultures of Kalanchoë gastonis-bonnieri Transformed by Agrobacterium rhizogenes

MG Barrera Núñez, M Bueno, MÁ Molina-Montiel… - Agronomy, 2024 - mdpi.com
Kalanchoë gastonis-bonnieri Raym.-Hamet & Perrier is a plant used for medicinal purposes
in the treatment of several ailments. The aim of this study was to analyze the chemical profile …