Innate immune evasion strategies of SARS-CoV-2
JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …
associated with substantial global morbidity and mortality. Despite a tropism that is largely …
Targeting the NLRP3 inflammasome in cardiovascular diseases
The NACHT, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …
Interleukin-1 and the NLRP3 inflammasome in COVID-19: Pathogenetic and therapeutic implications
A hyperinflammatory response during severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 …
(SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 …
The role of cell death in SARS-CoV-2 infection
C Yuan, Z Ma, J Xie, W Li, L Su, G Zhang, J Xu… - Signal transduction and …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …
Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine …
AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …
Cytokine storm syndrome in SARS-CoV-2 infections: a functional role of mast cells
Cytokine storm syndrome is a cascade of escalated immune responses disposing the
immune system to exhaustion, which might ultimately result in organ failure and fatal …
immune system to exhaustion, which might ultimately result in organ failure and fatal …
In silico drug repurposing carvedilol and its metabolites against SARS-CoV-2 infection using molecular docking and molecular dynamic simulation approaches
The pandemic of coronavirus disease 2019 (COVID-19) caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a significant impact on …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a significant impact on …
Cell deaths: Involvement in the pathogenesis and intervention therapy of COVID-19
X Li, Z Zhang, Z Wang… - Signal transduction and …, 2022 - nature.com
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has dramatically influenced …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has dramatically influenced …
NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis
N Potere, E Garrad, Y Kanthi, M Di Nisio… - Cardiovascular …, 2023 - academic.oup.com
Immunothrombosis—immune-mediated activation of coagulation—is protective against
pathogens, but excessive immunothrombosis can result in pathological thrombosis and …
pathogens, but excessive immunothrombosis can result in pathological thrombosis and …
Possible role of matrix metalloproteinases and TGF-β in COVID-19 severity and sequelae
G Ramírez-Martínez, LA Jiménez-Álvarez… - Journal of interferon & …, 2022 - liebertpub.com
The costs of coronavirus disease 2019 (COVID-19) are devastating. With millions of deaths
worldwide, specific serological biomarkers, antiviral agents, and novel therapies are …
worldwide, specific serological biomarkers, antiviral agents, and novel therapies are …