Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized as a
neoplastic disorder owing to the discovery of recurrent activating MAPK (RAS-RAF-MEK …

Context Rosai-Dorfman disease is an uncommon histiocytic disorder most frequently
presenting as bilateral cervical lymphadenopathy in children and young adults. Extranodal …

Histiocytoses constitute a heterogeneous group of rare disorders, characterised by
infiltration of almost any organ by myeloid cells with diverse macrophage or dendritic cell …

Histiocytic neoplasms are rare hematologic disorders accounting for less than 1% of cancers
of the soft tissue and lymph nodes. Clinical presentation and prognosis of these disorders …

Erdheim-Chester disease (ECD) is a rare, multisystemic, inflammatory, non–Langerhans cell
histiocytic neoplasm. The discovery of recurrent and somatic mutations in the mitogen …

Histiocytic neoplasms, a rare and heterogeneous group of disorders, primarily include
Erdheim-Chester disease, Langerhans cell histiocytosis, and Rosai-Dorfman disease. Due …

Rosai-Dorfman disease (RDD) is a rare histiocytosis with heterogenous clinical features. In
this study, we characterized the histologic and phenotypic features in 33 RDD patients to …

Histiocytoses are heterogeneous hematopoietic diseases characterized by the accumulation
of CD68 (+) cells with various admixed inflammatory infiltrates. The identification of the …

Simple Summary Rosai–Dorfman disease (RDD) was a benign histiocytic proliferative
disorder rather than a neoplastic process. Emergent molecular studies have shown …

Erdheim-Chester disease (ECD) is characterized by the infiltration of tissues by foamy
CD68+ CD1a− histiocytes, with 1500 known cases since 1930. Mutations activating the …