Many bacterial pathogens can permanently colonize their host and establish either chronic
or recurrent infections that the immune system and antimicrobial therapies fail to eradicate …

Aminoglycosides (AGs) are long-known molecules successfully used against Gram-negative
pathogens. While their use declined with the discovery of new antibiotics, they are now …

The development of effective treatments against infectious diseases is an extensive and
ongoing process due to the rapid adaptation of bacteria to antibiotic-based therapies …

The therapeutic arsenal against bacterial infections is rapidly shrinking, as drug resistance
spreads and pharmaceutical industry are struggling to produce new antibiotics. In this …

Due to the emergence of antimicrobial resistance, new alternative therapies are needed.
Silver was used to treat bacterial infections since antiquity due to its known antimicrobial …

Following the discovery of streptomycin from Streptomyces griseus in the 1940s by Selman
Waksman and colleagues, aminoglycosides were first used to treat tuberculosis and then …

Persistence is a phenomenon during which a small fraction of a total bacterial population
survives treatment with high concentrations of antibiotics for an extended period of time. In …

Introduction Increasing bacteria resistance to antibiotics is a major problem of healthcare
system. There is a need for solutions that broaden the spectrum of bactericidal agents …

Avian pathogenic Escherichia coli (APEC) causes colibacillosis in poultry, a leading cause
of poultry mortality worldwide. It is crucial to control APEC in broiler breeders as it is …

The bactericidal activity of silver nanoparticles is supported by a large number of studies, but
their action mechanisms are still a controversial issue due to the role of the silver (I) released …