Magnetic resonance imaging of placental intralobule structure and function in a preclinical nonhuman primate model

A Melbourne, MC Schabel, AL David… - Biology of …, 2024 - academic.oup.com
Although the central role of adequate blood flow and oxygen delivery is known, the lack of
optimized imaging modalities to study placental structure has impeded our understanding of …

Developments in functional imaging of the placenta

A Clark, D Flouri, N Mufti, J James… - The British Journal of …, 2023 - academic.oup.com
The placenta is both the literal and metaphorical black box of pregnancy. Measurement of
the function of the placenta has the potential to enhance our understanding of this enigmatic …

Normal human and sheep fetal vessel oxygen saturations by T2 magnetic resonance imaging

BS Saini, JRT Darby, S Portnoy, L Sun… - The Journal of …, 2020 - Wiley Online Library
Key points Human fetal Doppler ultrasound and invasive blood gas measurements obtained
by cordocentesis or at the time of delivery reveal similarities with sheep (an extensively used …

Placental MRI predicts fetal oxygenation and growth rates in sheep and human pregnancy

D Flouri, JRT Darby, SL Holman, SKS Cho… - Advanced …, 2022 - Wiley Online Library
Magnetic resonance imaging (MRI) assessment of fetal blood oxygen saturation (SO2) can
transform the clinical management of high‐risk pregnancies affected by fetal growth …

The effects of maternal position, in late gestation pregnancy, on placental blood flow and oxygenation: an MRI study

S Couper, A Clark, JMD Thompson… - The Journal of …, 2021 - Wiley Online Library
Key points Maternal supine sleep position in late pregnancy is associated with an increased
risk of stillbirth. Maternal supine position in late pregnancy reduces maternal cardiac output …

Assessing within‐subject rates of change of placental MRI diffusion metrics in normal pregnancy

D Cromb, PJ Slator, M De La Fuente… - Magnetic …, 2023 - Wiley Online Library
Purpose Studying placental development informs when development is abnormal. Most
placental MRI studies are cross‐sectional and do not study the extent of individual variability …

Perfusion fraction derived from IVIM analysis of diffusion-weighted MRI in the assessment of placental vascular malperfusion antenatally

M Malmberg, E Kragsterman, M Sinding, DN Hansen… - Placenta, 2022 - Elsevier
Introduction Specific placental pathologies that may impact fetal development, such as
vascular malperfusion, are diagnosed postpartum. We aimed to evaluate if placental …

Magnetic resonance imaging of placentome development in the pregnant Ewe

D Flouri, JRT Darby, SL Holman, SR Perumal… - Placenta, 2021 - Elsevier
Introduction Novel imaging measurements of placental development are difficult to validate
due to the invasive nature of gold-standard procedures. Animal studies have been important …

Deformable slice-to-volume registration for reconstruction of quantitative T2* placental and fetal MRI

A Uus, JK Steinweg, A Ho, LH Jackson… - Medical Ultrasound, and …, 2020 - Springer
Abstract In 4D T2* placental MRI studies, motion correction is generally considered a
prerequisite for quantitative analysis. However, the existing approaches use only global …

Can introvoxel incoherent motion MRI be used to differentiate patients with placenta accreta spectrum disorders?

T Lu, H Pu, K Li, J Mei, M Huang, S Wang - BMC Pregnancy and Childbirth, 2019 - Springer
Background The incidence of PAS disorders increased rapidly in recent years, and
introvoxel incoherent motion (IVIM) MRI has been applied in the assessment of placenta …