Purpose Nitazoxanide is a broad-spectrum antiparasitic that has been tested for COVID-19
due to its anti-inflammatory effects and in vitro antiviral activity. This study synthesized the …

Objective To evaluate whether the addition of colchicine to standard of care (SOC) results in
better outcomes in hospitalized patients with COVID-19. Design This interventional …

Objectives We conducted an updated systematic review and meta-analysis to investigate the
effect of colchicine treatment on clinical outcomes in patients with COVID-19. Design …

Objective To evaluate whether colchicine treatment was associated with the inhibition of
NLRP3 inflammasome activation in patients with COVID-19. Methods We present a post hoc …

Background. Despite significant improvements in both treatment and prevention strategies,
as well as multiple commissioned reviews, there remains uncertainty regarding the survival …

Background The association between N-acetylcysteine (NAC) and COVID-19 remains
undetermined; therefore, this meta-analysis assessed the clinical efficacy of NAC in the …

One of the therapeutic hallmarks of the ongoing (COVID-19) pandemic has been the
different iterations of successful and sometimes unsuccessful attempts at re-purposing of …

Background: The therapeutic potential of oral colchicine administration may help combat
COVID-19 infection due to reduced disease severity and mortality risk. Objective: This …

Background and purpose: Hypoxia can lead to body function impairment. It is linked to the
pathology of acute mountain sickness, cardiovascular disease, and stroke. Colchicine, an …

BackgroundDespite significant improvements in both treatment and prevention strategies, as
well as multiple commissioned reviews, there remains uncertainty regarding the survival …